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Completed Phase 2 Interventional Results available

Pembrolizumab +/- Bevacizumab for Recurrent GBM

ClinicalTrials.gov ID: NCT02337491

Public ClinicalTrials.gov record NCT02337491. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 8:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Study of Pembrolizumab (MK-3475) With and Without Bevacizumab for Recurrent Glioblastoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

In this research study, the investigators are looking to determine the effectiveness of Pembrolizumab (MK-3475) when given with bevacizumab or when given alone for the treatment of recurrent glioblastoma multiforme (GBM). This study will also test the safety and tolerability of Pembrolizumab (MK-3475) when given alone or with bevacizumab.

Study identification

NCT ID
NCT02337491
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
80 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 8, 2015
Primary completion
Aug 27, 2016
Completion
Sep 13, 2020
Last update posted
Dec 21, 2020

2015 – 2020

United States locations

U.S. sites
8
U.S. states
6
U.S. cities
7
Facility City State ZIP Site status
University of California, Los Angeles Los Angeles California 90095
University of California, San Francisco San Francisco California 94143-0372
Massachusetts General Hospital Boston Massachusetts 02113
Dana-Farber Cancer Institute Boston Massachusetts 02215
Memorial Sloan-Kettering Cancer New York New York 10021
Duke University Medical Center Durham North Carolina 27710
UT, MD Anderson Cancer Center Houston Texas 77030
Huntsman Cancer Institute Salt Lake City Utah 84112

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02337491, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 21, 2020 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02337491 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →