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Completed Phase 2 Interventional Results available

Phase 2 Randomized Clinical Trial of Luminate® as Compared to Avastin® in the Treatment of Diabetic Macular Edema

ClinicalTrials.gov ID: NCT02348918

Public ClinicalTrials.gov record NCT02348918. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:20 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Controlled, Double-Masked, Multicenter Clinical Trial Designed to Evaluate the Safety and Exploratory Efficacy of Luminate® (ALG-1001) as Compared to Avastin® in the Treatment of Diabetic Macular Edema (DME)

Study identification

NCT ID
NCT02348918
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Allegro Ophthalmics, LLC
Industry
Enrollment
218 participants

Conditions and interventions

Interventions

  • Avastin Drug
  • Luminate 0.5mg Drug
  • Luminate 1.0mg Drug
  • Luminate 2.0mg Drug
  • Luminate 3.0mg Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 12, 2014
Primary completion
May 15, 2017
Completion
Jun 12, 2017
Last update posted
Dec 6, 2018

2014 – 2017

United States locations

U.S. sites
17
U.S. states
11
U.S. cities
17
Facility City State ZIP Site status
Associated Retina Consultants Phoenix Arizona 85020
Retina Vitreous Associates Medical Group Beverly Hills California 90211
Northern California Retina Vitreous Associates Mountain View California 94040
West Coast Retina San Francisco California 94109
Orange County Retina Medical Group Santa Ana California 92705
New England Retina Associates New London Connecticut 06320
Florida Eye Clinic Altamonte Springs Florida 32701
Retina Specialty Institute Pensacola Florida 32503
Center for Retina and Macular Disease Winter Haven Florida 33880
Wilmer Eye Institute at John Hopkins University Baltimore Maryland 21205
TLC Eye Group Jackson Michigan 49202
Island Retina Shirley New York 11967
Charlotte EENT Associates Charlotte North Carolina 28210
Black Hills Regional Eye Institute Rapid City South Dakota 57701
Austin Retina Associates Austin Texas 78705
Retina Consultant of Houston Houston Texas 77098
Spokane Eye Clinical Research Spokane Washington 99204

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02348918, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 6, 2018 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02348918 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →