Efficacy and Safety Study of NKTR-181 in Opioid-Naive Subjects With Low Back Pain
Public ClinicalTrials.gov record NCT02362672. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of NKTR-181 in Opioid-Naive Subjects With Moderate to Severe Chronic Low Back Pain
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether a new opioid molecule, NKTR-181, is effective for the relief of moderate to severe chronic low back pain as compared to a placebo.
Study identification
- NCT ID
- NCT02362672
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,189 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 11, 2015 (Actual)
- Primary completion
- Dec 2016 (Actual)
- Completion
- Feb 2017 (Actual)
- Last update posted
- Sep 16, 2020
2015 – 2017
United States locations
- U.S. sites
- 54
- U.S. states
- 27
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigator Site - Saraland | Saraland | Alabama | 36571 | — |
| Investigator Site - Phoenix | Phoenix | Arizona | 85023 | — |
| Investigator Site - Tempe | Tempe | Arizona | 85283 | — |
| Investigator Site - Little Rock | Little Rock | Arkansas | 72211 | — |
| Investigator Site - Stamford | Stamford | Connecticut | 06905 | — |
| Investigator Site - Clearwater | Clearwater | Florida | 33765 | — |
| Investigator Site - Fort Lauderdale | Fort Lauderdale | Florida | 33312 | — |
| Investigator Site - Jacksonville | Jacksonville | Florida | 32257 | — |
| Investigator Site - Orlando | Orlando | Florida | 32806 | — |
| Investigator Site - Ormond Beach | Ormond Beach | Florida | 32174 | — |
| Investigator Site - Plantation | Plantation | Florida | 33324 | — |
| Investigator Site - Tampa | Tampa | Florida | 33603 | — |
| Investigator Site - West Palm Beach | West Palm Beach | Florida | 33409 | — |
| Investigator Site - Atlanta | Atlanta | Georgia | 30338 | — |
| Investigator Site - Blue Ridge | Blue Ridge | Georgia | 30513 | — |
| Investigator Site - Marietta | Marietta | Georgia | 30060 | — |
| Investigator Site - Norcross | Norcross | Georgia | 30092 | — |
| Investigator Site - Gurnee | Gurnee | Illinois | 60031 | — |
| Investigator Site - West Des Moines | West Des Moines | Iowa | 50265 | — |
| Investigator Site - Wichita | Wichita | Kansas | 67207 | — |
| Investigator Site - Louisville | Louisville | Kentucky | 40213 | — |
| Investigator Site - Bossier | Bossier City | Louisiana | 71111 | — |
| Investigator Site - New Orleans | New Orleans | Louisiana | 70115 | — |
| Investigator Site - Shreveport | Shreveport | Louisiana | 71105 | — |
| Investigator Site - Bay City | Bay City | Michigan | 48706 | — |
| Investigator Site - Pinconning | Pinconning | Michigan | 48706 | — |
| Investigator Site - Biloxi | Biloxi | Mississippi | 39531 | — |
| Investigator Site - Saint Louis 1 | St Louis | Missouri | 63141 | — |
| Investigator Site - Saint Louis 2 | St Louis | Missouri | 63141 | — |
| Investigator Site - Omaha | Omaha | Nebraska | 68134 | — |
| Investigator Site - Las Vegas 2 | Las Vegas | Nevada | 89102 | — |
| Investigator Site - Las Vegas 1 | Las Vegas | Nevada | 89119 | — |
| Investigator Site - Rochester | Rochester | New York | 14642 | — |
| Investigator Site - Williamsville | Williamsville | New York | 14221 | — |
| Investigator Site - Greensboro | Greensboro | North Carolina | 27410 | — |
| Investigator Site - Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| Investigator Site - Fargo | Fargo | North Dakota | 58104 | — |
| Investigator Site - Beavercreek | Beavercreek | Ohio | 45432 | — |
| Investigator Site - Cincinnati 1 | Cincinnati | Ohio | 45219 | — |
| Investigator Site - Cincinnati 2 | Cincinnati | Ohio | 45246 | — |
| Investigator Site - Columbus | Columbus | Ohio | 43235 | — |
| Investigator Site - Duncansville | Duncansville | Pennsylvania | 16635 | — |
| Investigator Site - Jenkintown | Jenkintown | Pennsylvania | 19046 | — |
| Investigator Site - Rapid City | Rapid City | South Dakota | 57702 | — |
| Investigator Site - Memphis | Memphis | Tennessee | 38119 | — |
| Investigator Site - Arlington | Arlington | Texas | 76012 | — |
| Investigator Site - Austin | Austin | Texas | 78731 | — |
| Investigator Site - Killeen | Killeen | Texas | 76543 | — |
| Investigator Site - San Antonio | San Antonio | Texas | 78229 | — |
| Investigator Site - Salt Lake City | Salt Lake City | Utah | 84124 | — |
| Investigator Site - West Jordan | West Jordan | Utah | 84088 | — |
| Investigator Site - Midlothian | Midlothian | Virginia | 23114 | — |
| Investigator Site - Norfolk | Norfolk | Virginia | 23507 | — |
| Investigator Site - Kenosha | Kenosha | Wisconsin | 53142 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02362672, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 16, 2020 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02362672 live on ClinicalTrials.gov.