A Study of Atezolizumab in Combination With Carboplatin Plus (+) Nab-Paclitaxel Compared With Carboplatin+Nab-Paclitaxel in Participants With Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Public ClinicalTrials.gov record NCT02367781. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Multicenter, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) in Combination With Carboplatin+Nab-Paclitaxel for Chemotherapy-Naive Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer
Study identification
- NCT ID
- NCT02367781
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 723 participants
Conditions and interventions
Conditions
Interventions
- Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody Drug
- Carboplatin Drug
- Nab-Paclitaxel Drug
- Pemetrexed Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 15, 2015
- Primary completion
- Mar 14, 2018
- Completion
- Jan 17, 2021
- Last update posted
- Aug 8, 2021
2015 – 2021
United States locations
- U.S. sites
- 57
- U.S. states
- 25
- U.S. cities
- 55
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Highlands Oncology Group | Springdale | Arkansas | 72762 | — |
| Kaiser Permanente Oakland Medical Center | Oakland | California | 94611 | — |
| Kaiser Permanente Medical Center - Roseville | Roseville | California | 95661 | — |
| Kaiser Permanente - Sacramento Medical Center and Medical Offices | Sacramento | California | 95825 | — |
| Kaiser Permanente - San Francisco Medical Center | San Francisco | California | 94118 | — |
| Kaiser Permanente - San Jose Medical Center | San Jose | California | 95119 | — |
| Kaiser Permanente - San Leandro Medical Center | San Leandro | California | 94577 | — |
| Kaiser Permanente - Santa Clara | Santa Clara | California | 95051 | — |
| Kaiser Permanente - South San Francisco | South San Francisco | California | 94080 | — |
| Kaiser Permanente; Oncology Clinical Trials | Vallejo | California | 94589 | — |
| Kaiser Permanente - Walnut Creek | Walnut Creek | California | 94596 | — |
| Banner MD Anderson Cancer Center | Greeley | Colorado | 85234 | — |
| Eastern Connecticut Hematology and Oncology Associates; (ECHO) | Norwich | Connecticut | 06360 | — |
| University of Miami School of Medicine - Sylvester at Deerfield | Deerfield Beach | Florida | Suite 200 | — |
| SCRI Florida Cancer Specialists South | Fort Myers | Florida | 33916 | — |
| Florida Hospital | Orlando | Florida | 32803 | — |
| Florida Cancer Specialists (St. Petersburg - St. Anthony's Professional Building) | St. Petersburg | Florida | 33705 | — |
| SCRI Florida Cancer Specialists East | West Palm Beach | Florida | 33401 | — |
| University Cancer & Blood Center, LLC; Research | Athens | Georgia | 30607 | — |
| Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital | Carrollton | Georgia | 30117 | — |
| Suburban Hematology / Oncology Associates | Lawrenceville | Georgia | 30046 | — |
| Southeastern Regional Medical Center, Inc. | Newnan | Georgia | 30265 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60612 | — |
| Joliet Oncology-Hematology; Associates, Ltd. | Joliet | Illinois | 60435 | — |
| Illinois Cancer Care | Peoria | Illinois | 61615 | — |
| Quincy Medical Group | Quincy | Illinois | 62301 | — |
| Southern Illinois University, Simmons Cancer Institute | Springfield | Illinois | 62794 | — |
| Fort Wayne Med Oncology & Hematology Inc | Fort Wayne | Indiana | 46845 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242-1083 | — |
| Lahey Clinic Med Ctr | Lexington | Kentucky | 02421 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20814 | — |
| Center For Cancer and Blood Disorders | Bethesda | Maryland | 20817 | — |
| Southcoast Health System | Fairhaven | Massachusetts | 02719 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Hematology and Oncology Associates at Bridgepoint | Tupelo | Mississippi | 38801 | — |
| Southeast Nebraska Cancer Ctr | Lincoln | Nebraska | 68510 | — |
| Va Sierra Nevada Health Care System | Reno | Nevada | 89502 | — |
| Englewood Hospital and Medical Center | Englewood | New Jersey | 07631 | — |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Cancer Inst. of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Laura and ISAAC Perlmutter Cancer Center at NYU Langone. | New York | New York | 10016 | — |
| Clinical Research Alliance | Westbury | New York | 11590 | — |
| Presbyterian Hospital | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center; Department of Medicine | Durham | North Carolina | 27710 | — |
| W.G. Bill Hefner VA Medical Center | Salisbury | North Carolina | — | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Mark H. Zangmeister Center | Columbus | Ohio | 43219 | — |
| Oncology Hematology Care, Inc. | Hamilton | Ohio | 45103 | — |
| Pinnacle Health | Harrisburg | Pennsylvania | 17110 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17604 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Greenville Health System; Cancer Center | Greenville | South Carolina | 29605-4292 | — |
| University Oncology Associates | Chattanooga | Tennessee | 37403 | — |
| SCRI Tennessee Oncology Chattanooga | Chattanooga | Tennessee | 37404 | — |
| SCRI The Center For Cancer and Blood Disorders | Denton | Texas | 76210 | — |
| University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | — |
| Cancer Care Network of South Texas - SAT & BC | San Antonio | Texas | 78217 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 75 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02367781, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 8, 2021 · Synced May 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02367781 live on ClinicalTrials.gov.