Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 3 Interventional Results available

Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer

ClinicalTrials.gov ID: NCT02369874

Public ClinicalTrials.gov record NCT02369874. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 11:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Randomized, Open-Label, Multi-Center, Global Study of MEDI4736 Monotherapy and MEDI4736 in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Study identification

NCT ID
NCT02369874
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
736 participants

Conditions and interventions

Interventions

  • MEDI4736 Drug
  • MEDI4736 + Tremelimumab Drug
  • Standard of Care Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 96 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 8, 2015
Primary completion
Sep 9, 2018
Completion
Nov 12, 2020
Last update posted
Feb 9, 2021

2015 – 2020

United States locations

U.S. sites
23
U.S. states
15
U.S. cities
21
Facility City State ZIP Site status
Research Site Tucson Arizona 85711
Research Site Fullerton California 92835-3825
Research Site Los Angeles California 90089
Research Site Redondo Beach California 90277
Research Site Stanford California 94305
Research Site Denver Colorado 80218
Research Site Newark Delaware 19713
Research Site Miami Beach Florida 33140
Research Site Orlando Florida 32806
Research Site Atlanta Georgia 30322
Research Site Evanston Illinois 60201-1718
Research Site Lexington Kentucky 40536
Research Site Boston Massachusetts 02215
Research Site Rochester New York 14621
Research Site Rochester New York 14642
Research Site Winston-Salem North Carolina 27157
Research Site Pittsburgh Pennsylvania 15232
Research Site Germantown Tennessee 38138
Research Site Nashville Tennessee 37232
Research Site Dallas Texas 75230
Research Site Dallas Texas 75246
Research Site McAllen Texas 78503
Research Site Norfolk Virginia 23502

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 145 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02369874, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 9, 2021 · Synced Jun 25, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02369874 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →