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Completed Not applicable Interventional

Saline Hypertonic in Preschoolers

ClinicalTrials.gov ID: NCT02378467

Public ClinicalTrials.gov record NCT02378467. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 1:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess whether inhalation of 7% hypertonic saline (HS) twice daily for 48 weeks improves the lung clearance index by multiple breath nitrogen washout in comparison with inhalation of 0.9% isotonic saline (IS) in preschool children (ages 3 to 5) with cystic fibrosis.

Study identification

NCT ID
NCT02378467
Recruitment status
Completed
Study type
Interventional
Phase
Not applicable
Enrollment
150 participants

Conditions and interventions

Eligibility (public fields only)

Age range
3 Years to 5 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2015
Primary completion
Aug 30, 2018
Completion
Aug 30, 2018
Last update posted
Jan 13, 2020

2015 – 2018

United States locations

U.S. sites
23
U.S. states
19
U.S. cities
23
Facility City State ZIP Site status
University of Alabama-Birmingham: Pulmonary, Allergy and Critical Care Medicine Birmingham Alabama 35233
Stanford University Palo Alto California 94304
Children's Hospital of Colorado Aurora Colorado 80045
Nemours Children's Hospital Orlando Florida 32827
Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois 60611
Riley Hospital for Children-Indiana U Med Center Indianapolis Indiana 46202
University of Iowa, Department of Pediatrics Iowa City Iowa 52242
Johns Hopkins University: Pediatric Pulmonary Baltimore Maryland 21287
Boston Children's Hospital Boston Massachusetts 02115
Children's Hospitals and Clinics of Minnesota Minneapolis Minnesota 55404
Children's Mercy Hospital Kansas City Missouri 64108
Washington University School of Medicine St Louis Missouri 63110
Women & Children's Hospital of Buffalo Buffalo New York 14222
University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599-7217
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Rainbow Babies Children's Hospital and Case Western Reserve University School of Medicine Cleveland Ohio 44212
Nationwide Children's Hospital Columbus Ohio 43205
Oregon Health Sciences University Portland Oregon 97239
Children's Hospital of Philadelphia, UPenn Philadelphia Pennsylvania 19104
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224
Texas Children's Hospital and Baylor College of Medicine Houston Texas 77030
Seattle Children's Hospital Seattle Washington 98105
Children's Hospital of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02378467, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 13, 2020 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02378467 live on ClinicalTrials.gov.

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