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Terminated Phase 1 Interventional

A Study of Varlilumab (Anti-CD27) and Sunitinib in Patients With Metastatic Clear Cell Renal Cell Carcinoma

ClinicalTrials.gov ID: NCT02386111

Public ClinicalTrials.gov record NCT02386111. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:14 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase l/ll Study of Varlilumab in Combination With Sunitinib in Patients With Metastatic Clear Cell Renal Cell Carcinoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a study to determine the clinical benefit (how well the drug works), safety, and tolerability of combining varlilumab and sunitinib. The study will enroll patients with metastatic clear cell renal cell carcinoma.

Study identification

NCT ID
NCT02386111
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Celldex Therapeutics
Industry
Enrollment
17 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 2015 (Type not available)
Primary completion
Aug 2017 (Actual)
Completion
Nov 3, 2017 (Actual)
Last update posted
Jul 26, 2018

2015 – 2017

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294 —
UC Davis Comprehensive Cancer Center Sacramento California 95817 —
UCSF Helen Diller Comprehensive Cancer Center San Francisco California 94158 —
George Washington University-Medical Faculty Associates Washington D.C. District of Columbia 20037 —
University of Michigan Ann Arbor Michigan 48109 —
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 —
Nebraska Cancer Specialists Omaha Nebraska 68130 —
Mount Sinai Medical Center New York New York 10029 —
Thomas Jefferson University Philadelphia Pennsylvania 19107 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02386111, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 26, 2018 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02386111 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →