A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer
Public ClinicalTrials.gov record NCT02399137. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine Versus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether the combination of MM-141 plus nab-paclitaxel and gemcitabine is more effective than nab-paclitaxel and gemcitabine alone based on Progression Free Survival (PFS) in front-line metastatic pancreatic cancer patients with high serum levels of free IGF-1.
Study identification
- NCT ID
- NCT02399137
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 88 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2015 (Type not available)
- Primary completion
- Aug 2018 (Actual)
- Completion
- Aug 2018 (Actual)
- Last update posted
- Sep 18, 2018
2015 – 2018
United States locations
- U.S. sites
- 47
- U.S. states
- 18
- U.S. cities
- 43
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner MD Anderson Cancer Ctr. | Gilbert | Arizona | 85234 | — |
| Pacific Cancer Medical Center, Inc. | Anaheim | California | 92801 | — |
| St. Jude Heritage Healthcare | Fullerton | California | 92835 | — |
| UCLA School of Medicine | Los Angeles | California | 90095 | — |
| Cancer Care Assoc Med Grp | Redondo Beach | California | 90277 | — |
| UCSF Cancer Center | San Francisco | California | 94115 | — |
| Sansum Clinic | Santa Barbara | California | 93105 | — |
| Central Coast Med Onc Corp | Santa Maria | California | 93454 | — |
| Rocky Mountain Cancer Centers | Aurora | Colorado | — | — |
| Baptist Health Med Gr Onc, LLC | Miami | Florida | — | — |
| Florida Cancer AffiliatesOcala | Ocala | Florida | — | — |
| Memorial Regional Hospital | Pembroke Pines | Florida | 33028 | — |
| Cancer Treatment Centers of America-Georgia | Newnan | Georgia | 30265 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60612 | — |
| Illinois Cancer Specialists | Chicago | Illinois | — | — |
| Oncology Specialists, S.C. | Park Ridge | Illinois | 60068 | — |
| Midwest Regional Medical Cntr | Zion | Illinois | — | — |
| Nylen Cancer Center | Sioux City | Iowa | — | — |
| Cancer Center of Acadiana Research Department | Lafayette | Louisiana | 70503 | — |
| Reliant Medical Group, Inc. | Worcester | Massachusetts | 01608 | — |
| Compr Cancer Centers of Nevada | Henderson | Nevada | — | — |
| New York Oncology HematologyPC | Albany | New York | — | — |
| Roswell Park Cancer Inst | Buffalo | New York | 14263 | — |
| Bassett Cancer Institute | Cooperstown | New York | — | — |
| North Shore Hematology Oncology Associates, PC | East Setauket | New York | 11733 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Columbia University | New York | New York | 10032 | — |
| Mid Ohio Onco/ Zangmeister Ctr | Columbus | Ohio | — | — |
| Tulsa Cancer Institute, PLLC | Tulsa | Oklahoma | — | — |
| St. Luke's University Health Network | Bethlehem | Pennsylvania | 18015 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Allegheny Cancer Center | Pittsburgh | Pennsylvania | — | — |
| Vanderbilt-Ingram Cancer Ctr | Nashville | Tennessee | 37232 | — |
| SCRI - Tennessee Oncology | Nashville | Tennessee | — | — |
| Texas Oncology-Austin Midtown | Austin | Texas | — | — |
| Texas Oncology P A Bedford | Bedford | Texas | — | — |
| Texas Oncology-Dallas P.H. | Dallas | Texas | — | — |
| Brooke Army Medical Center (BAMC) | Fort Sam Houston | Texas | 78234 | — |
| Texas Oncology-Paris | Paris | Texas | — | — |
| Texas Oncology-Plano East | Plano | Texas | — | — |
| Texas Oncology SA Medical Ctr | San Antonio | Texas | — | — |
| Texas Oncology-Tyler | Tyler | Texas | — | — |
| Virginia Cancer Specialists PC | Fairfax | Virginia | — | — |
| Onc and Hem Asso of SW VA Inc | Salem | Virginia | — | — |
| Cancer Care Northwest, P.S. | Spokane Valley | Washington | 99216 | — |
| Northwest Cancer SpecialistsPC | Vancouver | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02399137, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 18, 2018 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02399137 live on ClinicalTrials.gov.