An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients With Early-Stage HER2+ Breast Cancer Treated With Neratinib and Loperamide
Public ClinicalTrials.gov record NCT02400476. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
An Open-Label Study to Characterize the Incidence and Severity of Diarrhea in Patients with Early-Stage HER2+ Breast Cancer Treated with Neratinib and Loperamide or other prophylactic measures.
Study identification
- NCT ID
- NCT02400476
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 563 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2015 (Actual)
- Primary completion
- Apr 22, 2021 (Actual)
- Completion
- Apr 22, 2021 (Actual)
- Last update posted
- May 6, 2022
2015 – 2021
United States locations
- U.S. sites
- 39
- U.S. states
- 19
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Oncology | Birmingham | Alabama | 35205 | — |
| Compassionate Care Research Group Inc. | Corona | California | 92879 | — |
| St. Joseph Heritage Healthcare | Fullerton | California | 92835 | — |
| Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | — |
| Emad Ibrahim, M.D., Inc. | Redlands | California | 92373 | — |
| Torrance Memorial Physician Network Cancer Care Associates | Redondo Beach | California | 90277 | — |
| Compassionate Care Research Group Inc. | Riverside | California | 92501 | — |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| The Oncology Institute of Hope and Innovation | Santa Ana | California | 92705 | — |
| Cancer Center of Santa Barbara with Sansum Clinic | Santa Barbara | California | 93105 | — |
| Central Coast Medical Oncology Corporation | Santa Maria | California | 93454 | — |
| Memorial Healthcare System | Hollywood | Florida | 33021 | — |
| Florida Cancer Research Institute, LLC | Plantation | Florida | 33324 | — |
| Hematology-Oncology Associates of the Treasure Coast | Port Saint Lucie | Florida | 34952 | — |
| Baptist Health Urgent Care Sawgrass | Sunrise | Florida | 33322 | — |
| Cancer Treatment Centers of America | Newnan | Georgia | 30265 | — |
| Decatur Memorial Hospital Cancer Care Specialists of Central Illinois | Decatur | Illinois | 62526 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | — |
| Central Maine Medical Center | Lewiston | Maine | 04240 | — |
| University of Maryland, Greenebaum Comprehensive Cancer Center | Baltimore | Maryland | 21201 | — |
| North Mississippi Medical Center Hematology and Oncology Services | Tupelo | Mississippi | 38801 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Great Plains Health (Callahan Cancer Center) | North Platte | Nebraska | 69101 | — |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| MD Anderson Cancer Center at Cooper | Voorhees Township | New Jersey | 08035 | — |
| Clinical Research Alliance, Inc | Lake Success | New York | 11042 | — |
| Good Samaritan Hospital Samaritan Pastega Regional Cancer Center | Corvallis | Oregon | 97330 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Magee-Womens Hospital of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| Charleston Hematology Oncology Associates | Charleston | South Carolina | 29414 | — |
| Saint Joseph / Candler SC Cancer Specialists | Hilton Head Island | South Carolina | 29926 | — |
| Coastal Bend Cancer Center | Corpus Christi | Texas | 78412 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Community Cancer Trials of Utah | Ogden | Utah | 84405 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02400476, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2022 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02400476 live on ClinicalTrials.gov.