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Not listed Phase 3 Interventional

Study of EBI-005 in Dry Eye Disease (DED)

ClinicalTrials.gov ID: NCT02405039

Public ClinicalTrials.gov record NCT02405039. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Double-Masked, Randomized, One-Year Safety Study of EBI-005 5 mg/mL Topical Ophthalmic Solution Versus Vehicle-Control in Subjects With Dry Eye Disease (DED)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, double masked study designed to evaluate the safety of EBI-005 5 mg/mL topical ophthalmic solution given three times daily (TID) compared to vehicle-control over a one year period in subjects with dry eye disease (DED). Approximately 188 subjects will be enrolled to either EBI-005 or vehicle at up to 15 centers in the United States (US) and Canada.

Study identification

NCT ID
NCT02405039
Recruitment status
Not listed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Eleven Biotherapeutics
Industry
Enrollment
188 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2015
Primary completion
May 31, 2016
Completion
Jun 30, 2016
Last update posted
Jun 3, 2015

2015 – 2016

United States locations

U.S. sites
12
U.S. states
12
U.S. cities
12
Facility City State ZIP Site status
Not listed Birmingham Alabama 35294
Not listed Newport Beach California 92663
Not listed Hamden Connecticut 06518
Not listed New Albany Indiana 47150
Not listed Louisville Kentucky 40206
Not listed Winchester Massachusetts 01890
Not listed St Louis Missouri 63131
Not listed Asheville North Carolina 28803
Not listed Mason Ohio 45040
Not listed Cranberry Township Pennsylvania 16066
Not listed Memphis Tennessee 38119
Not listed San Antonio Texas 78229

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02405039, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 3, 2015 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02405039 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →