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Completed Phase 2 Interventional Results available

A Safety and Efficacy Study of NS2 in Patients With Anterior Uveitis

ClinicalTrials.gov ID: NCT02406209

Public ClinicalTrials.gov record NCT02406209. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 2:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Investigator-Masked, Comparator-controlled Trial to Evaluate the Safety and Efficacy of NS2 Eye Drops in Patients With Anterior Uveitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, multi-center, investigator masked, comparator controlled study. The purpose of this study is to determine the efficacy and safety of NS2 in patients with non-infectious acute anterior uveitis. Subjects will be randomized 1:1:1 to receive multiple doses of NS2 0.5%, NS2 0.5% and Pred Forte® 1%, or Pred Forte® 1%. Free aldehydes are thought to be related to inflammatory diseases such as uveitis. NS2, a small molecule aldehyde trap, may decrease inflammation by lowering aldehyde levels.

Study identification

NCT ID
NCT02406209
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Aldeyra Therapeutics, Inc.
Industry
Enrollment
45 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 2015 (Type not available)
Primary completion
Apr 2016 (Actual)
Completion
Apr 2016 (Actual)
Last update posted
Mar 27, 2023

2015 – 2016

United States locations

U.S. sites
15
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
Hull Eye Center Lancaster California 93534 —
Colorado Retina Associates,PC Golden Colorado 80401 —
Eye Center of Southern Connecticut Hamden Connecticut 06518-3144 —
Bascom Palmer Eye Institute Plantation Florida 33324 —
Valley Eye Physicians & Surgeons Ayer Massachusetts 01940 —
Ophthalmic Consultants of Boston Boston Massachusetts 02114 —
Massachusetts Eye Research and Surgery Institution (MERSI) Waltham Massachusetts 02451 —
Oakland Ophthalmic Surgery Birmingham Michigan 48009 —
Lifelong Vision Foundation Chesterfield Missouri 63017 —
Tauber Eye Center Kansas City Missouri 64111 —
UNMC Stanley Truhlsen Eye Institute Omaha Nebraska 68106 —
Metropolitan Eye Research & Surgery Institute Palisades Park New Jersey 07650 —
Mid-Atlantic Retina Philadelphia Pennsylvania 19107 —
Houston Eye Associates Houston Texas 77025 —
Virginia Eye Consultants Norfolk Virginia 23502 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02406209, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 27, 2023 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02406209 live on ClinicalTrials.gov.

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