Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
Public ClinicalTrials.gov record NCT02414269. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I/II Clinical Trial of Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
Study identification
- NCT ID
- NCT02414269
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Other
- Enrollment
- 113 participants
Conditions and interventions
Interventions
- iCasp9M28z T cell infusions Genetic
- cyclophosphamide Drug
- pembrolizumab Drug
Genetic · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2015
- Primary completion
- Apr 29, 2026
- Completion
- Apr 29, 2026
- Last update posted
- Oct 7, 2025
2015 – 2026
United States locations
- U.S. sites
- 6
- U.S. states
- 2
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Memorial Sloan Kettering Basking Ridge (Consent and Follow-Up) | Basking Ridge | New Jersey | — | — |
| Memorial Sloan Kettering Monmouth (Consent and Follow-Up) | Middletown | New Jersey | 07748 | — |
| Memorial Sloan Kettering Bergen (Consent and Follow-Up) | Montvale | New Jersey | 07645 | — |
| Memorial Sloan Kettering Commack (Consent and Follow-Up) | Commack | New York | — | — |
| Memorial Sloan Kettering Westchester (Consent and Follow-Up) | Harrison | New York | 10604 | — |
| Memorial Sloan Kettering Cancer Center (Consent and Follow-Up) | New York | New York | 10065 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02414269, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 7, 2025 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02414269 live on ClinicalTrials.gov.