A Study of Vonapanitase (PRT-201) Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-2)
Public ClinicalTrials.gov record NCT02414841. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicenter, Double Blind, Placebo Controlled Study of Vonapanitase (PRT- 201) Administered Immediately After Radiocephalic Arteriovenous Fistula Creation in Patients With Chronic Kidney Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This research study is designed to assess the safety and effectiveness of an experimental drug called vonapanitase (PRT-201) in patients both receiving or expecting to receive hemodialysis who have chronic kidney disease and who are undergoing surgery to create a new access point to their bloodstream for hemodialysis. Vonapanitase is a protein that has been shown in previous research studies to help keep vessels patent when applied to the outside surface of the blood vessels (arteries and veins) in patients who undergo surgery to create an arteriovenous fistula (AVF). The purpose of this study is to determine whether vonapanitase when applied to a limited segment of your blood vessel (about 2 inches) immediately after surgery is safe and improves the patency of your AVF.
Study identification
- NCT ID
- NCT02414841
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 696 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2015 (Actual)
- Primary completion
- Feb 2018 (Actual)
- Completion
- May 1, 2019 (Actual)
- Last update posted
- Aug 13, 2019
2015 – 2019
United States locations
- U.S. sites
- 36
- U.S. states
- 22
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| AKDHC Medical Research Services, LLC | Phoenix | Arizona | 85012 | — |
| Banner University Medical Center Tucson | Tucson | Arizona | 85724 | — |
| AKDHC Medical Research Services, LLc | Tucson | Arizona | 85745 | — |
| VA Loma Linda Healthcare System | Loma Linda | California | 92357 | — |
| VA Medical Center Long Beach | Long Beach | California | 90822 | — |
| Keck University Hospital at USC | Los Angeles | California | 90033 | — |
| Kaiser Permanente | San Diego | California | 92120 | — |
| California Institute of Renal Research | San Diego | California | 92123 | — |
| Kaiser Permanente Northern California | San Francisco | California | 94118 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| RenalCare Associates, S.C. | Peoria | Illinois | 61603 | — |
| Lutheran Hospital Network of Indiana | Fort Wayne | Indiana | 46804 | — |
| The University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Tulane University | New Orleans | Louisiana | 70112 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Massachusetts Medical Center | Worcester | Massachusetts | 01655 | — |
| VA Ann Arbor Healthcare System | Ann Arbor | Michigan | 48105 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Greenwood Leflore Hospital | Greenwood | Mississippi | 38930 | — |
| Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| New York Presbyterian Hospital-Weill Cornell Medical Center | New York | New York | 10065 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Wake Forest | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Lehigh Valley Health Network | Allentown | Pennsylvania | 18103 | — |
| VA Pittsburg Healthcare System | Pittsburgh | Pennsylvania | 15240 | — |
| SC Nephrology and Hypertension Center, Inc. | Orangeburg | South Carolina | 29118 | — |
| Knoxville Kidney Center | Knoxville | Tennessee | 37923 | — |
| Cardiothoracis and Vascular Surgeons | Austin | Texas | 78756 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| The Methodist Hospital | Houston | Texas | 77030 | — |
| Lake Washington Vascular Center | Bellevue | Washington | 98004 | — |
| University of Wisconsin School of Medicine and PH | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02414841, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 13, 2019 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02414841 live on ClinicalTrials.gov.