ClinicalTrials.gov record
Evaluation of Dupilumab in Patients With Persistent Asthma (Liberty Asthma Quest)
ClinicalTrials.gov ID: NCT02414854
Public ClinicalTrials.gov record NCT02414854. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Dupilumab in Patients With Persistent Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary Objective: To evaluate the efficacy of dupilumab (SAR231893 / REGN668) in participants with persistent asthma. Secondary Objectives: * To evaluate the safety and tolerability of dupilumab. * To evaluate the effect of dupilumab on improving participant-reported outcomes including health-related quality of life. * To evaluate dupilumab systemic exposure and incidence of anti-drug antibodies.
Study identification
- NCT ID
- NCT02414854
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,902 participants
Conditions and interventions
Conditions
Interventions
- Dupilumab Drug
- Placebo Drug
- Inhaled corticosteroid (ICS) therapy Drug
- Albuterol/Salbutamol Drug
- Levalbuterol/Levosalbutamol Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 27, 2015 (Type not available)
- Primary completion
- Jul 29, 2017 (Actual)
- Completion
- Nov 23, 2017 (Actual)
- Last update posted
- Oct 23, 2018
2015 – 2017
United States locations
- U.S. sites
- 116
- U.S. states
- 33
- U.S. cities
- 103
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site Number 840047 | Birmingham | Alabama | 35209 | — |
| Investigational Site Number 840056 | Flagstaff | Arizona | 86001 | — |
| Investigational Site Number 840099 | Gilbert | Arizona | 85234 | — |
| Investigational Site Number 840087 | Scottsdale | Arizona | 85251 | — |
| Investigational Site Number 840132 | Little Rock | Arkansas | 72209 | — |
| Investigational Site Number 840109 | Bakersfield | California | 93301 | — |
| Investigational Site Number 840052 | Costa Mesa | California | 92626 | — |
| Investigational Site Number 840116 | Fresno | California | 93720 | — |
| Investigational Site Number 840045 | Long Beach | California | 90720 | — |
| Investigational Site Number 840011 | Los Angeles | California | 90025 | — |
| Investigational Site Number 840061 | Los Angeles | California | 90048 | — |
| Investigational Site Number 840097 | Los Angeles | California | 90064 | — |
| Investigational Site Number 840019 | Mission Viejo | California | 92691 | — |
| Investigational Site Number 840125 | Newport Beach | California | 92663 | — |
| Investigational Site Number 840041 | North Hollywood | California | 91606 | — |
| Investigational Site Number 840036 | Redwood City | California | 94063 | — |
| Investigational Site Number 840020 | Rolling Hills Estates | California | 90274 | — |
| Investigational Site Number 840074 | Roseville | California | 95661 | — |
| Investigational Site Number 840021 | San Jose | California | 95117 | — |
| Investigational Site Number 840004 | Centennial | Colorado | 80112 | — |
| Investigational Site Number 840025 | Colorado Springs | Colorado | 80907 | — |
| Investigational Site Number 840034 | Denver | Colorado | 80230 | — |
| Investigational Site Number 840130 | Denver | Colorado | 80246 | — |
| Investigational Site Number 840102 | New Haven | Connecticut | 06504 | — |
| Investigational Site Number 840037 | Aventura | Florida | 33180 | — |
| Investigational Site Number 840018 | Boynton Beach | Florida | 33472 | — |
| Investigational Site Number 840105 | Brandon | Florida | 33511 | — |
| Investigational Site Number 840092 | Clearwater | Florida | 33765 | — |
| Investigational Site Number 840122 | Hialeah | Florida | 33012 | — |
| Investigational Site Number 840053 | Loxahatchee Groves | Florida | 33470 | — |
| Investigational Site Number 840069 | Miami | Florida | 33173 | — |
| Investigational Site Number 840123 | Ocala | Florida | 34471 | — |
| Investigational Site Number 840071 | Ocala | Florida | 34474 | — |
| Investigational Site Number 840115 | Ocoee | Florida | 34761 | — |
| Investigational Site Number 840055 | Sarasota | Florida | 34239 | — |
| Investigational Site Number 840114 | South Miami | Florida | 33143 | — |
| Investigational Site Number 840048 | Tampa | Florida | 33612 | — |
| Investigational Site Number 840084 | Gainesville | Georgia | 30506 | — |
| Investigational Site Number 840044 | Savannah | Georgia | 31406 | — |
| Investigational Site Number 840079 | Twin Falls | Idaho | 83301 | — |
| Investigational Site Number 840101 | Chicago | Illinois | 60611 | — |
| Investigational Site Number 840015 | River Forest | Illinois | 60305 | — |
| Investigational Site Number 840089 | Iowa City | Iowa | 52242 | — |
| Investigational Site Number 840032 | Fort Mitchell | Kentucky | 41017 | — |
| Investigational Site Number 840009 | Owensboro | Kentucky | 42303 | — |
| Investigational Site Number 840064 | Bangor | Maine | 04401 | — |
| Investigational Site Number 840080 | Baltimore | Maryland | 21237 | — |
| Investigational Site Number 840017 | Chevy Chase | Maryland | 20815 | — |
| Investigational Site Number 840073 | Gaithersburg | Maryland | 20878 | — |
| Investigational Site Number 840127 | White Marsh | Maryland | 21162 | — |
| Investigational Site Number 840014 | North Dartmouth | Massachusetts | 02747 | — |
| Investigational Site Number 840005 | Minneapolis | Minnesota | 55402 | — |
| Investigational Site Number 840013 | Kansas City | Missouri | 64111 | — |
| Investigational Site Number 840002 | St Louis | Missouri | 63141 | — |
| Investigational Site Number 840093 | St Louis | Missouri | 63141 | — |
| Investigational Site Number 840026 | Missoula | Montana | 59808 | — |
| Investigational Site Number 840078 | Omaha | Nebraska | 68131 | — |
| Investigational Site Number 840003 | Papillion | Nebraska | 27103 | — |
| Investigational Site Number 840111 | Brick | New Jersey | 08723 | — |
| Investigational Site Number 840068 | Ocean City | New Jersey | 07712 | — |
| Investigational Site Number 840016 | Princeton | New Jersey | 08540 | — |
| Investigational Site Number 840096 | Toms River | New Jersey | 08775 | — |
| Investigational Site Number 840106 | Jamaica | New York | 11435 | — |
| Investigational Site Number 840065 | New York | New York | 10029 | — |
| Investigational Site Number 840076 | Rochester | New York | 14642 | — |
| Investigational Site Number 840031 | The Bronx | New York | 10457 | — |
| Investigational Site Number 840126 | Charlotte | North Carolina | 28226 | — |
| Investigational Site Number 840083 | Charlotte | North Carolina | 28277 | — |
| Investigational Site Number 840108 | Durham | North Carolina | 27705 | — |
| Investigational Site Number 840107 | Greensboro | North Carolina | 27403 | — |
| Investigational Site Number 840007 | High Point | North Carolina | 27262 | — |
| Investigational Site Number 840046 | Cincinnati | Ohio | 45241 | — |
| Investigational Site Number 840049 | Middleburg Heights | Ohio | 44130 | — |
| Investigational Site Number 840042 | Toledo | Ohio | 43617 | — |
| Investigational Site Number 840112 | Edmond | Oklahoma | 73034 | — |
| Investigational Site Number 840121 | Oklahoma City | Oklahoma | 73103 | — |
| Investigational Site Number 840104 | Tulsa | Oklahoma | 74136 | — |
| Investigational Site Number 840040 | Clackamas | Oregon | 97015 | — |
| Investigational Site Number 840039 | Medford | Oregon | 97504 | — |
| Investigational Site Number 840001 | Portland | Oregon | 97223 | — |
| Investigational Site Number 840085 | Hershey | Pennsylvania | 17033 | — |
| Investigational Site Number 840081 | Philadelphia | Pennsylvania | 19102 | — |
| Investigational Site Number 840010 | Philadelphia | Pennsylvania | 19107 | — |
| Investigational Site Number 840067 | Philadelphia | Pennsylvania | 19140 | — |
| Investigational Site Number 840028 | Pittsburgh | Pennsylvania | 15213 | — |
| Investigational Site Number 840091 | Pittsburgh | Pennsylvania | 15241 | — |
| Investigational Site Number 840029 | Lincoln | Rhode Island | 02286 | — |
| Investigational Site Number 840082 | Charleston | South Carolina | 29407 | — |
| Investigational Site Number 840117 | Greenville | South Carolina | 29607 | — |
| Investigational Site Number 840100 | Greer | South Carolina | 29651 | — |
| Investigational Site Number 840054 | Spartanburg | South Carolina | 29303 | — |
| Investigational Site Number 840062 | Amarillo | Texas | 79106 | — |
| Investigational Site Number 840098 | Austin | Texas | 78759 | — |
| Investigational Site Number 840038 | Boerne | Texas | 78006 | — |
| Investigational Site Number 840124 | Cypress | Texas | 77429 | — |
| Investigational Site Number 840008 | Dallas | Texas | 75231 | — |
| Investigational Site Number 840094 | Dallas | Texas | 75246 | — |
| Investigational Site Number 840023 | El Paso | Texas | 79903 | — |
| Investigational Site Number 840022 | Fort Worth | Texas | 76109 | — |
| Investigational Site Number 840027 | Fort Worth | Texas | 76244 | — |
| Investigational Site Number 840066 | Killeen | Texas | 76542 | — |
| Investigational Site Number 840050 | Live Oak | Texas | 78233 | — |
| Investigational Site Number 840070 | McKinney | Texas | 75069 | — |
| Investigational Site Number 840128 | McKinney | Texas | 75071 | — |
| Investigational Site Number 840118 | Plano | Texas | 75093 | — |
| Investigational Site Number 840012 | San Antonio | Texas | 78229 | — |
| Investigational Site Number 840129 | San Antonio | Texas | 78251 | — |
| Investigational Site Number 840133 | Sealy | Texas | 77474 | — |
| Investigational Site Number 840119 | Spring | Texas | 77380 | — |
| Investigational Site Number 840035 | Draper | Utah | 84020 | — |
| Investigational Site Number 840077 | Murray | Utah | 84107 | — |
| Investigational Site Number 840057 | South Burlington | Vermont | 05403 | — |
| Investigational Site Number 840059 | Fairfax | Virginia | 22030 | — |
| Investigational Site Number 840113 | Richmond | Virginia | 23294 | — |
| Investigational Site Number 840051 | Bellevue | Washington | 98225 | — |
| Investigational Site Number 840043 | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 273 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02414854, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 23, 2018 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02414854 live on ClinicalTrials.gov.