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Terminated Phase 2 Interventional Results available

Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-Related Macular Degeneration (AMD)

ClinicalTrials.gov ID: NCT02418754

Public ClinicalTrials.gov record NCT02418754. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 7:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Double-Masked, Randomized, Controlled, Multiple-Dose, Regimen-Ranging Study of the Efficacy and Safety of Intravitreal REGN2176-3 in Patients With Neovascular Age-Related Macular Degeneration

Study identification

NCT ID
NCT02418754
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Regeneron Pharmaceuticals
Industry
Enrollment
505 participants

Conditions and interventions

Interventions

  • REGN2176-3 Drug
  • Intravitreal Aflibercept Injection (IAI) Drug

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 4, 2015
Primary completion
Aug 16, 2016
Completion
Apr 2, 2017
Last update posted
Oct 25, 2020

2015 – 2017

United States locations

U.S. sites
75
U.S. states
32
U.S. cities
75
Facility City State ZIP Site status
Not listed Phoenix Arizona
Not listed Tucson Arizona
Not listed Arcadia California
Not listed Beverly Hills California
Not listed Irvine California
Not listed Mountain View California
Not listed Oceanside California
Not listed Sacramento California
Not listed Santa Ana California
Not listed Colorado Springs Colorado
Not listed Fort Lauderdale Florida
Not listed Fort Myers Florida
Not listed Jacksonville Florida
Not listed Melbourne Florida
Not listed Miami Florida
Not listed Plantation Florida
Not listed Tampa Florida
Not listed Winter Haven Florida
Not listed Augusta Georgia
Not listed Marietta Georgia
Not listed Chicago Illinois
Not listed Oak Forest Illinois
Not listed Springfield Illinois
Not listed Urbana Illinois
Not listed Iowa City Iowa
Not listed Shawnee Mission Kansas
Not listed Lexington Kentucky
Not listed Paducah Kentucky
Not listed Baltimore Maryland
Not listed Towson Maryland
Not listed Boston Massachusetts
Not listed Jackson Michigan
Not listed Southfield Michigan
Not listed Minneapolis Minnesota
Not listed Florissant Missouri
Not listed Lincoln Nebraska
Not listed Omaha Nebraska
Not listed Las Vegas Nevada
Not listed Bloomfield New Jersey
Not listed New Brunswick New Jersey
Not listed Albuquerque New Mexico
Not listed Albany New York
Not listed East Setauket New York
Not listed Great Neck New York
Not listed New York New York
Not listed Orchard Park New York
Not listed Rochester New York
Not listed Asheville North Carolina
Not listed Charlotte North Carolina
Not listed Cincinnati Ohio
Not listed Oklahoma City Oklahoma
Not listed Portland Oregon
Not listed Kingston Pennsylvania
Not listed Monroeville Pennsylvania
Not listed Philadelphia Pennsylvania
Not listed Florence South Carolina
Not listed Ladson South Carolina
Not listed West Columbia South Carolina
Not listed Rapid City South Dakota
Not listed Knoxville Tennessee
Not listed Memphis Tennessee
Not listed Nashville Tennessee
Not listed Abilene Texas
Not listed Austin Texas
Not listed Dallas Texas
Not listed Fort Worth Texas
Not listed Houston Texas
Not listed McAllen Texas
Not listed San Antonio Texas
Not listed The Woodlands Texas
Not listed Willow Park Texas
Not listed Salt Lake City Utah
Not listed Burlington Vermont
Not listed Fairfax Virginia
Not listed Bellevue Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02418754, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 25, 2020 · Synced Jul 23, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02418754 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →