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Completed Phase 3 Interventional Results available

A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC)

ClinicalTrials.gov ID: NCT02420821

Public ClinicalTrials.gov record NCT02420821. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 12, 2026, 11:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Open-Label, Randomized Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Bevacizumab Versus Sunitinib in Patients With Untreated Advanced Renal Cell Carcinoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This multi-center, randomized, open-label study will evaluate the efficacy and safety of atezolizumab plus bevacizumab versus sunitinib in participants with inoperable, locally advanced, or metastatic RCC who have not received prior systemic active or experimental therapy, either in the adjuvant or metastatic setting.

Study identification

NCT ID
NCT02420821
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
915 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 19, 2015
Primary completion
Feb 13, 2020
Completion
Dec 12, 2021
Last update posted
Jan 29, 2023

2015 – 2021

United States locations

U.S. sites
28
U.S. states
18
U.S. cities
25
Facility City State ZIP Site status
University of Arizona Cancer Center Tucson Arizona 85719
University of California at Irvine Medical Center; Department of Oncology Orange California 92868
University of California San Francisco California 94158
University of Colorado; Anschutz Cancer Pavilion Aurora Colorado 80045
Rocky Mountain Cancer Center; Medical Oncology Boulder Colorado 80303
Georgetown U; Lombardi Comp Can Washington D.C. District of Columbia 20016-1468
Lynn Cancer Institute/Boca Raton Regional Hospital Boca Raton Florida 33486
Florida Cancer Specialists - Port Charlotte Port Charlotte Florida 33980
Florida Cancer Specialist, North Region St. Petersburg Florida 33705
Piedmont Cancer Institute, PC Atlanta Georgia 30318
The University of Chicago Chicago Illinois 60637
Norton Cancer Institute Louisville Kentucky 40202
Massachusetts General Hospital Boston Massachusetts 02114
Dana Farber Cancer Inst. Boston Massachusetts 02115
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
Comprehensive Cancer Centers of Nevada - Eastern Avenue Las Vegas Nevada 89169
Hackensack University Medical Center Hackensack New Jersey 07601
New York Oncology Hematology,P.C.-Albany Albany New York 12208
Memorial Sloan-Kettering Cancer Center New York New York 10065
Oncology Hematology Care Inc Cincinnati Ohio 45242
Cleveland Clinic Foundation; Taussig Cancer Center Cleveland Ohio 44195
Northwest Cancer Specialists, P.C. Tigard Oregon 97223
SCRI Tennessee Oncology Chattanooga Chattanooga Tennessee 37404
Sarah Cannon Cancer Center and Research Institute Nashville Tennessee 37203
Vanderbilt Univ Medical Ctr Nashville Tennessee 37232
Texas Oncology-Baylor Sammons Cancer Center Dallas Texas 75246
Oncology and Hematology Associates of SW Virginia-Raonoke Roanoke Virginia 24014
Seattle Cancer Care Alliance Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 126 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02420821, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 29, 2023 · Synced Sep 12, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02420821 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →