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Completed Phase 3 Interventional Results available

Clinical Trial of Lurbinectedin (PM01183) in Platinum Resistant Ovarian Cancer Patients

ClinicalTrials.gov ID: NCT02421588

Public ClinicalTrials.gov record NCT02421588. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 12:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase III Randomized Clinical Trial of Lurbinectedin (PM01183) Versus Pegylated Liposomal Doxorubicin or Topotecan in Patients With Platinum-resistant Ovarian Cancer (CORAIL Trial)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Multicenter, open-label, randomized, controlled phase III clinical trial to evaluate the activity and safety of PM01183 versus PLD or topotecan as control arm in patients with platinum-resistant ovarian cancer. PM01183 will be explored as single agent in the experimental arm (Arm A) versus PLD or topotecan in the control arm (Arm B).

Study identification

NCT ID
NCT02421588
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
PharmaMar
Industry
Enrollment
442 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2015
Primary completion
Oct 11, 2018
Completion
Oct 11, 2018
Last update posted
Apr 2, 2020

2015 – 2018

United States locations

U.S. sites
28
U.S. states
15
U.S. cities
26
Facility City State ZIP Site status
1112 Peoria Arizona
1102 Greenbrae California
1103 La Jolla California
1116 Los Angeles California
1120 Los Angeles California
1113 Palo Alto California
1111 San Francisco California
1122 Santa Maria California
1123 West Hills California
1109 Augusta Georgia
1104 Indianapolis Indiana
1110 Covington Louisiana
1124 Scarborough Maine
1121 Brick New Jersey
1127 Albany New York
1105 New York New York
1117 Asheville North Carolina
1101 Charlotte North Carolina
1125 Charlotte North Carolina
1108 Durham North Carolina
1107 Columbus Ohio
1118 Dayton Ohio
1119 Pittsburgh Pennsylvania
1115 Greenville South Carolina
1129 Nashville Tennessee
1131 Fort Worth Texas
1128 Houston Texas
1106 Charlottesville Virginia

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02421588, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 2, 2020 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02421588 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →