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Completed Phase 2 Interventional Results available

Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor

ClinicalTrials.gov ID: NCT02426086

Public ClinicalTrials.gov record NCT02426086. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 12:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Single-Blind, Multicenter Phase 2 Study to Evaluate the Activity of 2 Dose Levels of Imetelstat in Subjects With Intermediate-2 or High-Risk Myelofibrosis (MF) Relapsed/Refractory to Janus Kinase (JAK) Inhibitor

Study identification

NCT ID
NCT02426086
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Geron Corporation
Industry
Enrollment
107 participants

Conditions and interventions

Conditions

Interventions

  • Imetelstat 4.7 mg/kg Drug
  • Imetelstat 9.4 mg/kg Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 27, 2015
Primary completion
Apr 25, 2018
Completion
Feb 6, 2020
Last update posted
Sep 13, 2021

2015 – 2020

United States locations

U.S. sites
29
U.S. states
20
U.S. cities
29
Facility City State ZIP Site status
Not listed Birmingham Alabama
Not listed Duarte California
Not listed La Jolla California
Not listed Los Angeles California
Not listed Stanford California
Not listed Washington D.C. District of Columbia
Not listed Tampa Florida
Not listed West Palm Beach Florida
Not listed Chicago Illinois
Not listed Louisville Kentucky
Not listed Baltimore Maryland
Not listed Ann Arbor Michigan
Not listed Rochester Minnesota
Not listed St Louis Missouri
Not listed Buffalo New York
Not listed Lake Success New York
Not listed New York New York
Not listed The Bronx New York
Not listed Charlotte North Carolina
Not listed Durham North Carolina
Not listed Winston-Salem North Carolina
Not listed Cincinnati Ohio
Not listed Philadelphia Pennsylvania
Not listed Greenville South Carolina
Not listed Watertown South Dakota
Not listed Nashville Tennessee
Not listed Dallas Texas
Not listed Seattle Washington
Not listed Milwaukee Wisconsin

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 43 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02426086, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 13, 2021 · Synced Jul 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02426086 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →