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Completed Phase 2 Interventional Results available

A Study Assessing Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease

ClinicalTrials.gov ID: NCT02431468

Public ClinicalTrials.gov record NCT02431468. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 10:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind,Placebo-Controlled, Phase 2 Study Assessing the Safety, Tolerability and Efficacy of Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized double-blind placebo-controlled study comparing different doses of bryostatin for the treatment of moderately severe to severe Alzheimer's disease. The study is 15 weeks in duration, including a safety and efficacy evaluation 30 days after the last dose of study drug.

Study identification

NCT ID
NCT02431468
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Neurotrope Bioscience, Inc.
Industry
Enrollment
147 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
55 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2015 (Type not available)
Primary completion
Feb 2017 (Actual)
Completion
Feb 2017 (Actual)
Last update posted
Jul 6, 2018

2015 – 2017

United States locations

U.S. sites
29
U.S. states
16
U.S. cities
29
Facility City State ZIP Site status
Xenoscience, Inc/ 21st Century Neurology Phoenix Arizona 85004 —
ATP Clinical Research, Inc. Costa Mesa California 92626 —
Nader Pharmacology Research Institute Los Alamitos California 90720 —
San Francisco Clinical Research Center San Francisco California 94109 —
JEM Research Atlantis Florida 33462 —
Brain Matters Research Delray Beach Florida 33445 —
Neuropsychiatric Research Center of South Florida Fort Myers Florida 33912 —
Alzheimer's Research and Treatment Center Lake Worth Florida 33449 —
Miami Jewish Health System Miami Florida 33137 —
Medical Research Group of Central Florida Orange City Florida 32763 —
Compass Research, LLC Orlando Florida 32806 —
Axiom Clinical Research of Florida Tampa Florida 33609 —
Compass Research The Villages Florida 32162 —
Atlanta Center for Medical Research Atlanta Georgia 30331 —
iResearch Atlanta Decatur Georgia 30030 —
Alexian Brothers Neurosciences Institute Clinical Research Elk Grove Village Illinois 60007 —
University of Kansas Alzheimer's Disease Center Fairway Kansas 66205 —
Lake Charles Clinical Trials Lake Charles Louisiana 70629 —
J. Gary Booker, MD APMC Clinical Drug Trials Shreveport Louisiana 71104 —
Millennium Psychiatric Associates Creve Coeur Missouri 63141 —
Atlantic Neuroscience Institute Springfield New Jersey 07801 —
Neurological Associates of Albany, PC Albany New York 12208 —
Parker Jewish Institute for Health Care and Rehabilitation New Hyde Park New York 11040 —
Alzheimer's Memory Center Charlotte North Carolina 28270 —
Neurobehavioral Clinical Research Canton Ohio 44718 —
Oklahoma Clinical Research Center Oklahoma City Oklahoma 73112 —
Sunstone Clinical Research Medford Oregon 97504 —
The Clinical Trial Center, LLC Jenkintown Pennsylvania — —
Neurology Clinic, PC Cordova Tennessee 38018 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02431468, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 6, 2018 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02431468 live on ClinicalTrials.gov.

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