Study of Ibrutinib vs Placebo, in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma (RESOLVE)
Public ClinicalTrials.gov record NCT02436668. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Double-blind, Placebo-controlled, Phase 3 Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 3 study to evaluate the efficacy of ibrutinib in combination with nab-paclitaxel and gemcitabine for the first line treatment of patients with metastatic pancreatic adenocarcinoma.
Study identification
- NCT ID
- NCT02436668
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 430 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2015 (Type not available)
- Primary completion
- Oct 2018 (Actual)
- Completion
- Apr 25, 2019 (Actual)
- Last update posted
- Dec 30, 2020
2015 – 2019
United States locations
- U.S. sites
- 28
- U.S. states
- 19
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Oncology Specialties, PC; Clearview Cancer Institute | Huntsville | Alabama | 35805 | — |
| Arizona Center for Cancer Care | Avondale | Arizona | 85323 | — |
| St. Mary's Medical Center | Daly City | California | 94015 | — |
| Moores UCSD Cancer Center | La Jolla | California | 92093 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Eastern Connecticut Hematology/Oncology Assoc. | Norwich | Connecticut | 06360 | — |
| Bethesda Memorial Hospital | Boynton Beach | Florida | 33425 | — |
| Florida Hospital Tampa | Tampa | Florida | 33613 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Northwest Georgia Oncology Centers, PC | Marietta | Georgia | 30060 | — |
| Ingalls Memorial Hospital Cancer Research Center | Harvey | Illinois | 64026 | — |
| Joliet Oncology-Hematology Associates, LTD | Joliet | Illinois | 60435 | — |
| Investigative Clinical Research of Indiana | Indianapolis | Indiana | 46260 | — |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | — |
| Our Lady of the Lake Physician Group | Baton Rouge | Louisiana | 70809 | — |
| Center for Cancer and Blood Disorders | Bethesda | Maryland | 20817 | — |
| Berkshire Hematology Oncology Services at Berkshire Medical Center Cancer and Infusion Center | Pittsfield | Massachusetts | 01201 | — |
| Saint Joseph Mercy Health System | Chelsea | Michigan | 48118 | — |
| Sparrow Regional Cancer Center | Lansing | Michigan | 48912 | — |
| Nebraska Medicine - Peggy D. Cowdery Patient Care Center | Omaha | Nebraska | 68198 | — |
| The Presbyterian Hospital | Charlotte | North Carolina | 28204 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45267 | — |
| Penn State University Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Gibbs Cancer Center | Spartanburg | South Carolina | 29303 | — |
| Scott & White Memorial Hospital | Temple | Texas | 76508 | — |
| MultiCare Health System Institute for Research and Innovation | Tacoma | Washington | 98405 | — |
| Wenatchee Valley Hospital & Clinics | Wenatchee | Washington | 98801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 58 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02436668, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 30, 2020 · Synced Sep 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02436668 live on ClinicalTrials.gov.