A Neoadjuvant Study of Abemaciclib (LY2835219) in Postmenopausal Women With Hormone Receptor Positive, HER2 Negative Breast Cancer
Public ClinicalTrials.gov record NCT02441946. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
neoMONARCH: A Phase 2 Neoadjuvant Trial Comparing the Biological Effects of 2 Weeks of Abemaciclib (LY2835219) in Combination With Anastrozole to Those of Abemaciclib Monotherapy and Anastrozole Monotherapy and Evaluating the Clinical Activity and Safety of a Subsequent 14 Weeks of Therapy With Abemaciclib in Combination With Anastrozole in Postmenopausal Women With Hormone Receptor Positive, HER2 Negative Breast Cancer
Study identification
- NCT ID
- NCT02441946
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Eli Lilly and Company
- Industry
- Enrollment
- 224 participants
Conditions and interventions
Interventions
- Abemaciclib Drug
- Anastrozole Drug
- Loperamide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2015
- Primary completion
- Aug 15, 2016
- Completion
- Feb 11, 2018
- Last update posted
- Jun 16, 2020
2015 – 2018
United States locations
- U.S. sites
- 27
- U.S. states
- 14
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| University of California-San Diego | La Jolla | California | 92037-0845 | — |
| SMO TRIO -Translational Research | Los Angeles | California | 90024 | — |
| UCLA Medical Center | Los Angeles | California | 90024 | — |
| Cancer Care Associates Medical Group | Redondo Beach | California | 90277 | — |
| Sansum Medical Research Foundation | Santa Barbara | California | 93105 | — |
| Central Coast Medical Oncology Corporation | Santa Monica | California | 93454 | — |
| Stanford University | Stanford | California | 94305 | — |
| SMO Pharmatech Oncology Inc | Denver | Colorado | 80203 | — |
| St Mary's Hospital Regional Cancer Center | Grand Junction | Colorado | 81501 | — |
| Holy Cross Hospital Inc. | Fort Lauderdale | Florida | 33308 | — |
| Memorial Regional Hospital/Joe Dimaggio Childrens Hospital | Hollywood | Florida | 33021 | — |
| Oncology and Radiation Associates | Miami | Florida | 33133 | — |
| Orlando Health, Inc | Orlando | Florida | 32806 | — |
| Florida Cancer Research Institute | Plantation | Florida | 33324 | — |
| Northeast Georgia Cancer Care, LLC | Athens | Georgia | 30607 | — |
| Georgia Regents University | Augusta | Georgia | 30912 | — |
| Kaiser Foundation Hospitals | Honolulu | Hawaii | 96819 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| University of Massachusetts Medical Center | Worcester | Massachusetts | 80203 | — |
| Nebraska Hematology-Oncology | Lincoln | Nebraska | 68506 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| St. Charles Health System | Bend | Oregon | 97701 | — |
| The West Clinic | Germantown | Tennessee | 38138 | — |
| Millennium Oncology | Houston | Texas | 77090 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| Columbia Basin Hematology & Oncology | Kennewick | Washington | 99336 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02441946, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 16, 2020 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02441946 live on ClinicalTrials.gov.