ClinicalTrials.gov record
Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
ClinicalTrials.gov ID: NCT02442765
Public ClinicalTrials.gov record NCT02442765. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 (Deuterated [d6]-Dextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Participants with agitation secondary to dementia of the Alzheimer's type. The diagnosis of probable Alzheimer's disease (AD) was to be based on the "2011 Diagnostic Guidelines for Alzheimer's Disease" issued by the National Institute on Aging (NIA)-Alzheimer's Association (AA) workgroups.
Study identification
- NCT ID
- NCT02442765
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 387 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 22, 2015
- Primary completion
- Jan 29, 2019
- Completion
- Feb 26, 2019
- Last update posted
- Feb 12, 2023
2015 – 2019
United States locations
- U.S. sites
- 111
- U.S. states
- 28
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Site | Phoenix | Arizona | 85032 | — |
| Clinical Research Site | Scottsdale | Arizona | 85254 | — |
| Clinical Research Site | Little Rock | Arkansas | 72209 | — |
| Clinical Research Site#1 | Irvine | California | 92697 | — |
| Clinical Research Site#2 | Irvine | California | 92697 | — |
| Clinical Research Site | Long Beach | California | 90806 | — |
| Clinical Research Site | Oceanside | California | 92056 | — |
| Clinical Research Site | Orange | California | 92868 | — |
| Clinical Research Site#1 | San Diego | California | 92103 | — |
| Clinical Research Site#2 | San Diego | California | 92103 | — |
| Clinical Research Site | Santa Ana | California | 92704 | — |
| Clinical Research Site | Tustin | California | 92780 | — |
| Clinical Research Site | Denver | Colorado | 80209 | — |
| Clinical Research Site | Cromwell | Connecticut | 06416 | — |
| Clinical Research Site | New London | Connecticut | 06320 | — |
| Clinical Research Site | Norwalk | Connecticut | 06851 | — |
| Clinical Research Site | Atlantis | Florida | 33462 | — |
| Clinical Research Site | Boca Raton | Florida | 33428 | — |
| Clinical Research Site | Brandon | Florida | 33511 | — |
| Clinical Research Site#1 | Coral Gables | Florida | 33134 | — |
| Clinical Research Site#2 | Coral Gables | Florida | 33134 | — |
| Clinical Research Site#3 | Coral Gables | Florida | 33134 | — |
| Clinical Research Site#1 | Deerfield Beach | Florida | 33064 | — |
| Clinical Research Site | Doral | Florida | 33166 | — |
| Clinical Research Site | Hialeah | Florida | 33012 | — |
| Clinical Research Site#1 | Hialeah | Florida | 33016 | — |
| Clinical Research Site#2 | Hialeah | Florida | 33016 | — |
| Clinical Research Site | Jacksonville | Florida | 32256 | — |
| Clinical Research Site | Kendall | Florida | 33175 | — |
| Clinical Research Site | Kissimmee | Florida | 34741 | — |
| Clinical Research Site | Kissimmee | Florida | 34744 | — |
| Clinical Research Site | Lake Worth | Florida | 33449 | — |
| Clinical Research Site | Miami | Florida | 33122 | — |
| Clinical Research Site#1 | Miami | Florida | 33125 | — |
| Clinical Research Site#2 | Miami | Florida | 33125 | — |
| Clinical Research Site | Miami | Florida | 33126 | — |
| Clinical Research Site | Miami | Florida | 33133 | — |
| Clinical Research Site#1 | Miami | Florida | 33135 | — |
| Clinical Research Site#2 | Miami | Florida | 33135 | — |
| Clinical Research Site | Miami | Florida | 33136 | — |
| Clinical Research Site | Miami | Florida | 33137 | — |
| Clinical Research Site | Miami | Florida | 33144 | — |
| Clinical Research Site | Miami | Florida | 33145 | — |
| Clinical Research Site | Miami | Florida | 33165 | — |
| Clinical Research Site | Miami | Florida | 33175 | — |
| Clinical Research Site#2 | Miami | Florida | 33176 | — |
| Clinical Research Site | Miami | Florida | 33183 | — |
| Clinical Research Site | Miami | Florida | 33467 | — |
| Clinical Research Site | Naples | Florida | 34102 | — |
| Clinical Research Site | Oakland Park | Florida | 33334 | — |
| Clinical Research Site | Orlando | Florida | 32819 | — |
| Clinical Research Site | Ormond Beach | Florida | 32174 | — |
| Clinical Research Site | Palm Beach Gardens | Florida | 33410 | — |
| Clinical Research Site | Palmetto Bay | Florida | 33157 | — |
| Clinical Research Site#2 | Pompano Beach | Florida | 33064 | — |
| Clinical Research Site | Sarasota | Florida | 34243 | — |
| Clinical Research Site | St. Petersburg | Florida | 33713 | — |
| Clinical Research Site#1 | Tampa | Florida | 33609 | — |
| Clinical Research Site#2 | Tampa | Florida | 33609 | — |
| Clinical Research Site#2 | Tampa | Florida | 33613 | — |
| Clinical Research Site | Tampa | Florida | 33634 | — |
| Clinical Research Site | The Villages | Florida | 32162 | — |
| Clinical Research Site | West Palm Beach | Florida | 33407 | — |
| Clinical Research Site | Winter Park | Florida | 32789 | — |
| Clinical Research Site | Atlanta | Georgia | 30342 | — |
| Clinical Research Site | Newnan | Georgia | 30265 | — |
| Clinical Research Site | Honolulu | Hawaii | 96817 | — |
| Clinical Research Site | Schaumburg | Illinois | 60194 | — |
| Clinical Research Site | Indianapolis | Indiana | 46202 | — |
| Clinical Research Site | Lenexa | Kansas | 66214 | — |
| Clinical Research Site | Paducah | Kentucky | 42003 | — |
| Clinical Research Site | Bedford | Massachusetts | 01730 | — |
| Clinical Research Site | Quincy | Massachusetts | 02169 | — |
| Clinical Research Site | Ann Arbor | Michigan | 48105 | — |
| Clinical Research Site | Paw Paw | Michigan | 49079 | — |
| Clinical Research Site | Hattiesburg | Mississippi | 39401 | — |
| Clinical Research Site | Creve Coeur | Missouri | 63141 | — |
| Clinical Research Site | St Louis | Missouri | 63128 | — |
| Clinical Research Site | Mount Arlington | New Jersey | 07856 | — |
| Clinical Research Site | Toms River | New Jersey | 08755 | — |
| Clinical Research Site | West Long Branch | New Jersey | 07764 | — |
| Clinical Research Site | Amherst | New York | 14226 | — |
| Clinical Research Site | Brooklyn | New York | 11229 | — |
| Clinical Research Site | New York | New York | 10032 | — |
| Clinical Research Site | New York | New York | 10036 | — |
| Clinical Research Site | Orangeburg | New York | 10962 | — |
| Clinical Research Site | Rochester | New York | 14620 | — |
| Clinical Research Site | Staten Island | New York | 10312 | — |
| Clinical Research Site | Durham | North Carolina | 27710 | — |
| Clinical Research Site | Winston-Salem | North Carolina | 27157 | — |
| Clinical Research Site | Akron | Ohio | 44320 | — |
| Clinical Research Site | Cincinnati | Ohio | 45219 | — |
| Clinical Research Site#1 | Columbus | Ohio | 43210 | — |
| Clinical Research Site#2 | Columbus | Ohio | 43210 | — |
| Clinical Research Site | Dayton | Ohio | 45459 | — |
| Clinical Research Site | Westerville | Ohio | 43082 | — |
| Clinical Research Site | Edmond | Oklahoma | 73012 | — |
| Clinical Research Site | Oklahoma City | Oklahoma | 73103 | — |
| Clinical Research Site | Oklahoma City | Oklahoma | 73106 | — |
| Clinical Research Site | Oklahoma City | Oklahoma | 73112 | — |
| Clinical Research Site | Moosic | Pennsylvania | 18507 | — |
| Clinical Research Site | Willow Grove | Pennsylvania | 19090 | — |
| Clinical Research Site | East Providence | Rhode Island | 02914 | — |
| Clinical Research Site | Charleston | South Carolina | 29401 | — |
| Clinical Research Site#2 | Cordova | Tennessee | 38018 | — |
| Clinical Research Site | Dallas | Texas | 75231 | — |
| Clinical Research Site | Dallas | Texas | 75390-8898 | — |
| Clinical Research Site | Irving | Texas | 75062 | — |
| Clinical Research Site | Mansfield | Texas | 76063 | — |
| Clinical Research Site | Clinton | Utah | 84015 | — |
| Clinical Research Site | Woodstock | Vermont | 05091 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02442765, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 12, 2023 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02442765 live on ClinicalTrials.gov.