EMPIRE CF: A Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 in Adult Cystic Fibrosis (CF) Patients
Public ClinicalTrials.gov record NCT02443688. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 Administered Orally Once-Daily for 48 Weeks in Adult Patients With Cystic Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a Phase 2, double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy of CTX-4430 administered once-daily for 48 weeks for treatment of CF.
Study identification
- NCT ID
- NCT02443688
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 30 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 30, 2015 (Actual)
- Primary completion
- Apr 20, 2018 (Actual)
- Completion
- May 16, 2018 (Actual)
- Last update posted
- Sep 4, 2019
2015 – 2018
United States locations
- U.S. sites
- 39
- U.S. states
- 26
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35233 | — |
| Providence Health and Services | Anchorage | Alaska | 99508 | — |
| Banner University of Arizona Medical Center | Tucson | Arizona | 85724 | — |
| Childrens Hospital Los Angeles | Los Angeles | California | 90027 | — |
| Pediatric Pulmonary and Cystic Fibrosis Clinic, Stanford University | Palo Alto | California | 94304 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Central Florida Pulmonary Group | Orlando | Florida | 32803 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| St. Francis Medical Center | Peoria | Illinois | 61637 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Maine Medical Center | Portland | Maine | 04106 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan | Ann Arbor | Michigan | 49286 | — |
| Harper University Hospital | Detroit | Michigan | 48201 | — |
| Spectrum Health Butterworth Campus | Grand Rapids | Michigan | 49546 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Wake Forest Hospital | Winston-Salem | North Carolina | 27157 | — |
| UC Cincinnati Children's Hospital | Cincinnati | Ohio | 45267 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Oregon Health & Sciences University | Portland | Oregon | 97239 | — |
| Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Drexel University | Philadelphia | Pennsylvania | 19104 | — |
| The Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh | Pennsylvania | 15224 | — |
| Sanford Clinical Research | Sioux Falls | South Dakota | 57104 | — |
| Universiy of Tennessee Medical Center UHS | Knoxville | Tennessee | 37920 | — |
| Dell Children's Medical Center | Austin | Texas | 78723 | — |
| Cook Children's Hospital | Fort Worth | Texas | 76104 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02443688, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 4, 2019 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02443688 live on ClinicalTrials.gov.