Efficacy and Safety of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus
Public ClinicalTrials.gov record NCT02446899. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Randomised, Double-blind, Placebo-controlled, Phase 3 Study Evaluating the Efficacy and Safety of Anifrolumab in Adult Subjects With Active Systemic Lupus Erythematosus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of an intravenous treatment regimen of anifrolumab versus placebo in adult participants with moderately to severely active, autoantibody-positive systemic lupus erythematosus (SLE).
Study identification
- NCT ID
- NCT02446899
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 373 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 9, 2015 (Actual)
- Primary completion
- Sep 27, 2018 (Actual)
- Completion
- Sep 27, 2018 (Actual)
- Last update posted
- Jan 10, 2023
2015 – 2018
United States locations
- U.S. sites
- 35
- U.S. states
- 17
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Covina | California | 91723 | — |
| Research Site | Hemet | California | 92543-4403 | — |
| Research Site | Los Angeles | California | 90095 | — |
| Research Site | San Leandro | California | 94578 | — |
| Research Site | Torrance | California | 90509 | — |
| Research Site | Upland | California | 91786 | — |
| Research Site | Denver | Colorado | 80230 | — |
| Research Site | Bridgeport | Connecticut | 06606 | — |
| Research Site | Bridgeport | Connecticut | 6606 | — |
| Research Site | Brandon | Florida | 33511 | — |
| Research Site | Orlando | Florida | 32804 | — |
| Research Site | Palm Harbor | Florida | 34684 | — |
| Research Site | Tamarac | Florida | 33321 | — |
| Research Site | Tampa | Florida | 33614 | — |
| Research Site | Atlanta | Georgia | 30303 | — |
| Research Site | Boston | Massachusetts | 02118 | — |
| Research Site | Ann Arbor | Michigan | 48109 | — |
| Research Site | Lincoln | Nebraska | 68516 | — |
| Research Site | Las Cruces | New Mexico | 88011 | — |
| Research Site | Brooklyn | New York | 11201 | — |
| Research Site | New York | New York | 10016 | — |
| Research Site | New York | New York | 10021 | — |
| Research Site | New York | New York | 10032 | — |
| Research Site | Greenville | North Carolina | 27834 | — |
| Research Site | Oklahoma City | Oklahoma | 73104 | — |
| Research Site | Duncansville | Pennsylvania | 16635 | — |
| Research Site | Pittsburgh | Pennsylvania | 15213 | — |
| Research Site | Memphis | Tennessee | 38163 | — |
| Research Site | Dallas | Texas | 75231 | — |
| Research Site | Houston | Texas | 77004 | — |
| Research Site | Houston | Texas | 77034 | — |
| Research Site | Stafford | Texas | 77477 | — |
| Research Site | Arlington | Virginia | 22205 | — |
| Research Site | Seattle | Washington | 98122 | — |
| Research Site | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 78 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02446899, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 10, 2023 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02446899 live on ClinicalTrials.gov.