Efficacy and Safety of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus
Public ClinicalTrials.gov record NCT02446912. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Randomised, Double-blind, Placebo-controlled, Phase 3 Study Evaluating the Efficacy and Safety of Two Doses of Anifrolumab in Adult Subjects With Active Systemic Lupus Erythematosus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of an intravenous treatment regimen of two doses of anifrolumab versus placebo in adult subjects with moderately to severely active, autoantibody-positive systemic lupus erythematosus (SLE).
Study identification
- NCT ID
- NCT02446912
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 460 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 9, 2015 (Actual)
- Primary completion
- Jul 17, 2018 (Actual)
- Completion
- Jul 17, 2018 (Actual)
- Last update posted
- Jan 12, 2023
2015 – 2018
United States locations
- U.S. sites
- 52
- U.S. states
- 21
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35233 | — |
| Research Site | El Cajon | California | 91942-3191 | — |
| Research Site | La Jolla | California | 92037-0706 | — |
| Research Site | Los Alamitos | California | 90720 | — |
| Research Site | Thousand Oaks | California | 91360 | — |
| Research Site | Aurora | Colorado | 80045 | — |
| Research Site | Aventura | Florida | 33180 | — |
| Research Site | Miami | Florida | 33136 | — |
| Research Site | Orlando | Florida | 32804 | — |
| Research Site | Orlando | Florida | 32806 | — |
| Research Site | Ormond Beach | Florida | 32174 | — |
| Research Site | Plantation | Florida | 33324 | — |
| Research Site | Tampa | Florida | 33614 | — |
| Research Site | Vero Beach | Florida | 32960 | — |
| Research Site | Decatur | Georgia | 30033 | — |
| Research Site | Lawrenceville | Georgia | 30046 | — |
| Research Site | Marietta | Georgia | 30060 | — |
| Research Site | Boise | Idaho | 83712 | — |
| Research Site | Idaho Falls | Idaho | 83404 | — |
| Research Site | Baton Rouge | Louisiana | 70809 | — |
| Research Site | Hagerstown | Maryland | 21502 | — |
| Research Site | Hagerstown | Maryland | 21740 | — |
| Research Site | Grand Rapids | Michigan | 49546 | — |
| Research Site | Minneapolis | Minnesota | 55455-0341 | — |
| Research Site | Nashua | New Hampshire | 03060 | — |
| Research Site | Freehold | New Jersey | 07728 | — |
| Research Site | Great Neck | New York | 11021 | — |
| Research Site | New Hyde Park | New York | 11042 | — |
| Research Site | Charlotte | North Carolina | 28204 | — |
| Research Site | Charlotte | North Carolina | 28210 | — |
| Research Site | Raleigh | North Carolina | 27617 | — |
| Research Site | Cleveland | Ohio | 44109 | — |
| Research Site | Middleburg Heights | Ohio | 44130 | — |
| Research Site | Oklahoma City | Oklahoma | 73101 | — |
| Research Site | Tulsa | Oklahoma | 74104 | — |
| Research Site | Philadelphia | Pennsylvania | 19140 | — |
| Research Site | Pittsburgh | Pennsylvania | 15224 | — |
| Research Site | Wyomissing | Pennsylvania | 19610 | — |
| Research Site | Charleston | South Carolina | 29406 | — |
| Research Site | Charleston | South Carolina | 29407 | — |
| Research Site | Charleston | South Carolina | 29425 | — |
| Research Site | Jackson | Tennessee | 38305 | — |
| Research Site | Memphis | Tennessee | 38119 | — |
| Research Site | Amarillo | Texas | 79124 | — |
| Research Site | Austin | Texas | 78731 | — |
| Research Site | Austin | Texas | 78745 | — |
| Research Site | Dallas | Texas | 75231 | — |
| Research Site | Houston | Texas | 77074 | — |
| Research Site | Houston | Texas | 77099 | — |
| Research Site | Mesquite | Texas | 75150 | — |
| Research Site | San Antonio | Texas | 78232 | — |
| Research Site | Glendale | Wisconsin | 53217 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 93 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02446912, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 12, 2023 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02446912 live on ClinicalTrials.gov.