Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patients
Public ClinicalTrials.gov record NCT02453386. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of Tozadenant as Adjunctive Therapy in Levodopa-Treated Patients With Parkinson's Disease Experiencing End of Dose "Wearing-Off" (TOZ-PD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase 3, international, multicenter, randomized, double-blind, placebo-controlled, parallel-group, 3-arm safety and efficacy study (Part A) with an open-label phase (Part B).
Study identification
- NCT ID
- NCT02453386
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 449 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2015
- Primary completion
- Jan 11, 2018
- Completion
- Jan 11, 2018
- Last update posted
- Apr 2, 2019
2015 – 2018
United States locations
- U.S. sites
- 40
- U.S. states
- 24
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35005 | — |
| Not listed | Sun City | Arizona | 85351 | — |
| Not listed | Loma Linda | California | 92318 | — |
| Not listed | Los Angeles | California | 90001 | — |
| Not listed | Oxnard | California | 93030 | — |
| Not listed | Reseda | California | 91335 | — |
| Not listed | Sacramento | California | 914203 | — |
| Not listed | Sunnyvale | California | 94043 | — |
| Not listed | Englewood | Colorado | 80110 | — |
| Not listed | Vernon | Connecticut | 06029 | — |
| Not listed | Boca Raton | Florida | 33428 | — |
| Not listed | Gainesville | Florida | 32601 | — |
| Not listed | Jacksonville | Florida | 32034 | — |
| Not listed | Tampa | Florida | 33601 | — |
| Not listed | Atlanta | Georgia | 30301 | — |
| Not listed | Augusta | Georgia | 30805 | — |
| Not listed | Chicago | Illinois | 60007 | — |
| Not listed | Kansas City | Kansas | 66012 | — |
| Not listed | Lexington | Kentucky | 40502 | — |
| Not listed | Baltimore | Maryland | 21201 | — |
| Not listed | Boston | Massachusetts | 02101 | — |
| Not listed | East Lansing | Michigan | 48808 | — |
| Not listed | Farmington Hills | Michigan | 48167 | — |
| Not listed | West Bloomfield | Michigan | 48302 | — |
| Not listed | St Louis | Missouri | 63101 | — |
| Not listed | Albany | New York | 12084 | — |
| Not listed | Commack | New York | 11725 | — |
| Not listed | Rochester | New York | 14602 | — |
| Not listed | Asheville | North Carolina | 28715 | — |
| Not listed | Durham | North Carolina | 27517 | — |
| Not listed | Cincinnati | Ohio | 41073 | — |
| Not listed | Cleveland | Ohio | 44101 | — |
| Not listed | Toledo | Ohio | 43460 | — |
| Not listed | Tulsa | Oklahoma | 74008 | — |
| Not listed | Philadelphia | Pennsylvania | 19019 | — |
| Not listed | Nashville | Tennessee | 37011 | — |
| Not listed | Houston | Texas | 77001 | — |
| Not listed | Burlington | Vermont | 05401 | — |
| Not listed | Roanoke | Virginia | 24001 | — |
| Not listed | Kirkland | Washington | 98033 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02453386, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 2, 2019 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02453386 live on ClinicalTrials.gov.