A Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma
Public ClinicalTrials.gov record NCT02455245. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is trying to learn and understand if the chemotherapy drug called carboplatin works as well as the standard therapy. The standard therapy for Low Grade Glioma (LGG) in children and young adults is using a combination of carboplatin and vincristine. Studies in children have shown that the use of carboplatin alone has promise of being just as effective for treating LGG as standard therapy. Additionally, this study will try to understand if treatment with carboplatin alone is associated with an improved quality of life for LGG patients and their families.
Study identification
- NCT ID
- NCT02455245
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 95 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Up to 21 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2015 (Actual)
- Primary completion
- Aug 31, 2025 (Actual)
- Completion
- Nov 30, 2025 (Actual)
- Last update posted
- Sep 2, 2026
2015 – 2025
United States locations
- U.S. sites
- 21
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hospital | Phoeniz | Arizona | 85016 | — |
| Rady Children's Hospital | San Diego | California | 92123 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Orlando Health, Inc. | Orlando | Florida | 32806 | — |
| Ann & Robert H. Lurie Children's Hosptial of Chicago | Chicago | Illinois | 60611 | — |
| St. Vincent Peyton Manning Children's Hospital | Indianapolis | Indiana | 46260 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| The Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Michigan, C.S. Mott Children's Hospital | Ann Arbor | Michigan | 48109-5652 | — |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Minneapolis | Minnesota | 55404 | — |
| Saint Louis University at SSM Cardinal Glennon Children's Medical Center | St Louis | Missouri | 63103-2006 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110-1010 | — |
| Albany Medical Center | Albany | New York | 12208-3479 | — |
| Duke University Medical School | Durham | North Carolina | 27705-4682 | — |
| Children's Hospital Medical Center of Akron | Akron | Ohio | 44308-1062 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | — |
| Dayton Children's Hospital | Dayton | Ohio | 45404-1815 | — |
| American Family Children's Hospital | Madison | Wisconsin | 53792 | — |
| Medical College of Wiscosin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02455245, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 2, 2026 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02455245 live on ClinicalTrials.gov.