Safety, Tolerability, and Efficacy of GS-4997 Alone or in Combination With Simtuzumab (SIM) in Adults With Nonalcoholic Steatohepatitis (NASH) and Fibrosis Stages F2-F3
Public ClinicalTrials.gov record NCT02466516. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Open Label Study Evaluating the Safety, Tolerability, and Efficacy of GS-4997 Alone or in Combination With Simtuzumab (SIM) in Subjects With Nonalcoholic Steatohepatitis (NASH) and Fibrosis Stages F2-F3
Study identification
- NCT ID
- NCT02466516
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Gilead Sciences
- Industry
- Enrollment
- 72 participants
Conditions and interventions
Conditions
Interventions
- SEL Drug
- SIM Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 7, 2015
- Primary completion
- Oct 10, 2016
- Completion
- Oct 10, 2016
- Last update posted
- Jun 25, 2019
2015 – 2016
United States locations
- U.S. sites
- 26
- U.S. states
- 13
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| University of California San Diego | San Diego | California | 92103 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Duke University Medical Center | Durham | North Carolina | 03125 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburg Medical Center | Pittsburgh | Pennsylvania | 15143 | — |
| Texas Clinical Research Institute | Arlington | Texas | 76012 | — |
| Methodist Dallas Medical Center | Dallas | Texas | 75203 | — |
| CHI St. Luke's Health Baylor College of Medicine | Houston | Texas | 77030 | — |
| Brooke Army Medical Center Ft. Sam | Houston | Texas | 78234 | — |
| Digestive Research Center | Live Oak | Texas | 78233 | — |
| American Research Corporation at Texas Liver Institute | San Antonio | Texas | 78215 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Mary Immaculate Hospital | Newport News | Virginia | 23602 | — |
| St. Mary's Hospital | Richmond | Virginia | 23226 | — |
| Virginia Commonwealth University Health System | Richmond | Virginia | 23298 | — |
| Swedish Medical Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02466516, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2019 · Synced Jul 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02466516 live on ClinicalTrials.gov.