Efficacy, Safety and Tolerability Study of APL-130277 for the Acute Treatment of OFF Episodes in Patients With Parkinson's Disease
Public ClinicalTrials.gov record NCT02469090. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Examine the Efficacy, Safety and Tolerability of APL-130277 in Levodopa Responsive Patients With Parkinson's Disease Complicated by Motor Fluctuations ("OFF" Episodes)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A 12-week, prospective, multi-center, randomized, double-blind, placebo controlled, Phase 3 study in L-Dopa responsive PD patients with motor fluctuations ("OFF" episodes), designed to determine the efficacy, safety and tolerability of APL-130277.
Study identification
- NCT ID
- NCT02469090
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 141 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 18, 2015 (Actual)
- Primary completion
- Dec 11, 2017 (Actual)
- Completion
- Dec 11, 2017 (Actual)
- Last update posted
- Jul 30, 2020
2015 – 2017
United States locations
- U.S. sites
- 32
- U.S. states
- 18
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama, Birmingham | Birmingham | Alabama | 35233 | — |
| Muhammed Ali Parkinson and Movement Disorder CenterBarrow Neurological | Phoenix | Arizona | — | — |
| Movement Disorders Center of Arizona | Scottsdale | Arizona | 85258 | — |
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| The Parkinson's and Movement Disorder Institute | Fountain Valley | California | 92708 | — |
| UC Irvine Health Gottschalk Medical Plaza | Irvine | California | 92697 | — |
| Keck Medical Center at USC | Los Angeles | California | 90033 | — |
| The Research Center of Southern California | Oceanside | California | 92056 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Parkinsons Disease and Movement Disorders Center | Boca Raton | Florida | 33486 | — |
| University of Miami, Miller School of Medicine | Miami | Florida | 33136 | — |
| Parkinson's Disease Treatment Center of Southwest Florida | Port Charlotte | Florida | 33980 | — |
| USF Parkinson's Disease and Movement Disorder Center | Tampa | Florida | 33613 | — |
| Emory University Department of Neurology | Atlanta | Georgia | 30329 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Central DuPage Hospital - Neurodegenerative Clinic - Movement Disorders Center | Winfield | Illinois | 60190 | — |
| Kansas University Medical Center - Department of Neurology | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| QUEST Research Institute | Farmington Hills | Michigan | 48334 | — |
| Northern Michigan Neurology | Traverse City | Michigan | 49684 | — |
| Henry Ford Hospital | West Bloomfield | Michigan | 48322 | — |
| Columbia University Medical Center - Neurological Institute, Movement Disorders | New York | New York | 10032 | — |
| Raleigh Neurology Associates, P.A. | Raleigh | North Carolina | 27607 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Movement Disorder Clinic of Oklahoma | Tulsa | Oklahoma | 74136 | — |
| Jefferson University Hospital Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| University of Virginia, Adult Neurology | Charlottesville | Virginia | 22903 | — |
| Evergreen Health | Kirkland | Washington | 98034 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02469090, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 30, 2020 · Synced Oct 31, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02469090 live on ClinicalTrials.gov.