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Completed Phase 1 Interventional

PLX3397, Radiation Therapy, and Antihormone Therapy in Treating Patients With Intermediate- or High-Risk Prostate Cancer

ClinicalTrials.gov ID: NCT02472275

Public ClinicalTrials.gov record NCT02472275. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Targeting the Prostatic Tumor Microenvironment With PLX3397, a Tumor-Associated Macrophage Inhibitor in Men With Unfavorable Risk Prostate Cancer Undergoing Radiation Therapy and Androgen Deprivation Therapy

Study identification

NCT ID
NCT02472275
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Enrollment
8 participants

Conditions and interventions

Interventions

  • Antiandrogen Therapy Drug
  • Laboratory Biomarker Analysis Other
  • Multitargeted Tyrosine Kinase Inhibitor PLX3397 Drug
  • Radiation Therapy Radiation

Drug · Other · Radiation

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2015
Primary completion
Aug 4, 2019
Completion
Aug 4, 2019
Last update posted
Oct 5, 2020

2015 – 2019

United States locations

U.S. sites
3
U.S. states
1
U.S. cities
2
Facility City State ZIP Site status
Wayne State University/Karmanos Cancer Institute Detroit Michigan 48201
Karmanos Cancer Institute at McLaren Northern Michigan - Petoskey Radiation Oncology Petoskey Michigan 49770
Karmanos Cancer Institute at McLaren Northern Michigan- Petoskey Medical Oncology Petoskey Michigan 49770

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02472275, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 5, 2020 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02472275 live on ClinicalTrials.gov.

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