A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi
Public ClinicalTrials.gov record NCT02481674. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multi-center, Randomized, Double-blind, Placebo Controlled Study in Subjects With Late Prodromal and Early Manifest Huntington's Disease to Assess the Safety, Tolerability, pk, and Efficacy of Pepinemab
Study identification
- NCT ID
- NCT02481674
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Vaccinex Inc.
- Industry
- Enrollment
- 301 participants
Conditions and interventions
Conditions
Interventions
- VX15/2503 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2015
- Primary completion
- Jul 31, 2020
- Completion
- Jul 31, 2020
- Last update posted
- May 1, 2022
2015 – 2020
United States locations
- U.S. sites
- 29
- U.S. states
- 21
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| University of California, San Diego | La Jolla | California | 92037 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| University of Colorado - Denver | Aurora | Colorado | 80045 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| University of Florida Gainesville | Gainesville | Florida | 32611 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30329 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Johns Hopkins University | Baltimore | Maryland | 21218 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Massachusetts General Hospital | Charlestown | Massachusetts | 02129 | — |
| University of Michigan | Ann Arbor | Michigan | 48105 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Columbia University | New York | New York | 10027 | — |
| Columbia University | New York | New York | 10032 | — |
| University of Rochester | Rochester | New York | 14618 | — |
| Duke University Health Center | Durham | North Carolina | 27705 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| University of Toledo | Toledo | Ohio | 43614 | — |
| Vanderbilt University | Nashville | Tennessee | 37232 | — |
| University of Texas Houston Medical School | Houston | Texas | 77030 | — |
| University of Vermont | Burlington | Vermont | 05401 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| University of Washington and VA Puget Sound Health Care System | Seattle | Washington | 98195 | — |
| University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02481674, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 1, 2022 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02481674 live on ClinicalTrials.gov.