A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10
Public ClinicalTrials.gov record NCT02482441. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10 in Advanced Solid Tumors and in Combination With FOLFIRI for Patients With Previously Treated Metastatic Colorectal Cancer
Study identification
- NCT ID
- NCT02482441
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- OncoMed Pharmaceuticals, Inc.
- Industry
- Enrollment
- 50 participants
Conditions and interventions
Conditions
Interventions
- FOLFIRI Drug
- OMP-131R10 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 15, 2015
- Primary completion
- Jan 25, 2018
- Completion
- Mar 27, 2018
- Last update posted
- Aug 10, 2020
2015 – 2018
United States locations
- U.S. sites
- 7
- U.S. states
- 7
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCSF | San Francisco | California | 95115 | — |
| University of Colorado Hospital Anschulz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| Yale | New Haven | Connecticut | 06520-8028 | — |
| Massachusetts General Hospital, Dana Farber Cancer Institute | Boston | Massachusetts | 02114 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| The Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | — |
| M.D. Anderson Cancer Center | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02482441, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 10, 2020 · Synced May 11, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02482441 live on ClinicalTrials.gov.