Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year
Public ClinicalTrials.gov record NCT02496767. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multi-National, Double-Blind, Randomized, Placebo-Controlled, Stratified, Parallel Group, Study to Evaluate the Safety, Tolerability and Efficacy of Tirasemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study assessed the effect of tirasemtiv versus placebo on respiratory function in patients with ALS.
Study identification
- NCT ID
- NCT02496767
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 744 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 3, 2015 (Actual)
- Primary completion
- Mar 9, 2017 (Actual)
- Completion
- Sep 27, 2017 (Actual)
- Last update posted
- Sep 9, 2020
2015 – 2017
United States locations
- U.S. sites
- 49
- U.S. states
- 29
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph's Hospital & Medical Center - Barrow Neurology Clinics | Phoenix | Arizona | 85013 | — |
| University of California San Diego | La Jolla | California | 92093 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California, Irvine | Orange | California | 92868 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| Forbes Norris MDA/ALS Research Center | San Francisco | California | 94115 | — |
| Stanford Hospital and Clinics | Stanford | California | 94305 | — |
| University of Colorado Hospital Anschutz Outpatient Pavilion | Aurora | Colorado | 80045 | — |
| Hospital for Special Care | New Britain | Connecticut | 06053 | — |
| George Washington University Medical Center | Washington D.C. | District of Columbia | 20037 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Carol and Frank Morsini Center for Advanced Health Care - University of South Florida | Tampa | Florida | 33612 | — |
| The Emory Clinic | Atlanta | Georgia | 30322 | — |
| Georgia Regents University | Augusta | Georgia | 30912 | — |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| University of Michigan Hospital and Health System | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Neurology Associates | Lincoln | Nebraska | 68506 | — |
| Dartmouth Hitchcock Medical Center Dept of Neurology | Lebanon | New Hampshire | 03756 | — |
| Hospital for Special Surgery | New York | New York | 10021 | — |
| Neurological Institute Columbia University Medical Center | New York | New York | 10032 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Neurosciences Institute: Neurology - Charlotte | Charlotte | North Carolina | 28207 | — |
| Duke Neurological Disorders Clinic | Durham | North Carolina | 27705 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43221 | — |
| Providence Brain and Spine Institute ALS Center | Portland | Oregon | 97213 | — |
| Oregon Health and Science Center | Portland | Oregon | 97239 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| The Penn Comprehensive Neuroscience Center | Philadelphia | Pennsylvania | 19107 | — |
| Temple University School of Medicine | Philadelphia | Pennsylvania | 19140 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Texas Neurology | Dallas | Texas | 75214 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Texas Health Science Center | San Antonio | Texas | 78229 | — |
| University of Virgina Health System | Charlottesville | Virginia | 22908 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| West Virginia University Department of Neurology | Morgantown | West Virginia | 26506 | — |
| Froedtert Memorial Lutheran Hospital, Department of Neurology | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02496767, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2020 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02496767 live on ClinicalTrials.gov.