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Completed Phase 2 Interventional Results available

Safety And Efficacy Study Of Palbociclib Plus Cetuximab Versus Cetuximab To Treat Head And Neck Cancer

ClinicalTrials.gov ID: NCT02499120

Public ClinicalTrials.gov record NCT02499120. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 6:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A RANDOMIZED, MULTICENTER, DOUBLE-BLIND PHASE 2 STUDY OF PALBOCICLIB PLUS CETUXIMAB VERSUS CETUXIMAB FOR THE TREATMENT OF HUMAN PAPILLOMAVIRUS-NEGATIVE, CETUXIMAB-NAÏVE PATIENTS WITH RECURRENT/METASTATIC SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK AFTER FAILURE OF ONE PRIOR PLATINUM-CONTAINING CHEMOTHERAPY REGIMEN

Study identification

NCT ID
NCT02499120
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
125 participants

Conditions and interventions

Interventions

  • Cetuximab Drug
  • Placebo Drug
  • palbociclib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 9, 2015
Primary completion
Jul 18, 2018
Completion
Sep 6, 2022
Last update posted
Sep 7, 2023

2015 – 2022

United States locations

U.S. sites
14
U.S. states
6
U.S. cities
10
Facility City State ZIP Site status
UC San Diego Medical Center - La Jolla (Thornton Hospital) La Jolla California 92037
UC San Diego Moores Cancer Center La Jolla California 92093
UC San Diego Medical Center- Hillcrest San Diego California 92103
University Medical Center, lnc.:DBA University of Louisville Hospital Louisville Kentucky 40202
Mayo Clinic Rochester Minnesota 55905
Siteman Cancer Center City of Saint Peters Missouri 63376
Siteman Cancer Center - West County Creve Coeur Missouri 63141
Barnes-Jewish Hospital St Louis Missouri 63110
Washington University School of Medicine, Siteman Cancer Center St Louis Missouri 63110
Siteman Cancer Center - South County St Louis Missouri 63129
University of Cincinnati Investigational Pharmacy Cincinnati Ohio 45219
University of Cincinnati Medical Center Cincinnati Ohio 45219
UC Health Physicians Office South West Chester Ohio 45069
Henry Joyce Cancer Clinic Nashville Tennessee 37232

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 57 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02499120, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 7, 2023 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02499120 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →