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Completed Phase 1 Interventional

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

ClinicalTrials.gov ID: NCT02502708

Public ClinicalTrials.gov record NCT02502708. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 5:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I Trial of Indoximod and Temozolomide-Based Therapy for Children With Progressive Primary Brain Tumors

Study identification

NCT ID
NCT02502708
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
NewLink Genetics Corporation
Industry
Enrollment
81 participants

Conditions and interventions

Interventions

  • Indoximod Drug
  • Temozolomide Drug
  • Conformal Radiation Radiation
  • Cyclophosphamide Drug
  • Etoposide Drug

Drug · Radiation

Eligibility (public fields only)

Age range
3 Years to 21 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2015
Primary completion
Dec 11, 2019
Completion
Feb 27, 2020
Last update posted
Jun 3, 2020

2015 – 2020

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
Children's Hospital Colorado Aurora Colorado 80045
Arnold Palmer Hospital for Children Orlando Florida 32806
Children's Heathcare of Atlanta Atlanta Georgia 30342
Augusta University Augusta Georgia 30912
Children's Hospitals and Clinics of Minnesota Minneapolis Minnesota 55404

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02502708, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 3, 2020 · Synced Jun 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02502708 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →