Study of Pegcetacoplan (APL-2) Therapy in Patients With Geographic Atrophy
Public ClinicalTrials.gov record NCT02503332. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Randomized, Single-Masked, Sham-Controlled Study of Safety, Tolerability and Evidence of Activity of Intravitreal APL-2 Therapy in Patients With Geographic Atrophy (GA)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives of the study are to assess the safety, tolerability and evidence of activity of multiple intravitreal (IVT) injections of pegcetacoplan in subjects with Geographic Atrophy associated with Age-Related Macular Degeneration (AMD).
Study identification
- NCT ID
- NCT02503332
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 246 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 24, 2015 (Actual)
- Primary completion
- Jul 14, 2017 (Actual)
- Completion
- Jan 17, 2018 (Actual)
- Last update posted
- Oct 6, 2020
2015 – 2018
United States locations
- U.S. sites
- 35
- U.S. states
- 21
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Speciality Institute | Mobile | Alabama | 36606 | — |
| Retinal Research Institute | Phoenix | Arizona | 85014 | — |
| Retina Vitreous Asociates Mdical Goup | Beverly Hills | California | 90211 | — |
| The Gavin Herbert Eye Institute/UC Irvine | Irvine | California | 92697 | — |
| University of Southern California - USC Eye Institute | Los Angeles | California | 90033 | — |
| Byers Eye Institute at Stanford, Stanford School of Medicine | Palo Alto | California | 94303 | — |
| New England Retina Associates | New London | Connecticut | 06320 | — |
| Florida Eye Microsurgical Institute, Inc. | Boynton Beach | Florida | 33426 | — |
| Retina Health Center | Fort Myers | Florida | 33907 | — |
| Bascom Palmer Eye Institute | Miami | Florida | 33136 | — |
| South East Retina | Augusta | Georgia | 30909 | — |
| Illinois Retina Associates | Harvey | Illinois | 60426 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Elman Research | Baltimore | Maryland | 21237 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Associated Retinal Consultants PC | Grand Rapids | Michigan | 45946 | — |
| Associated Retinal Consultants, PC | Traverse City | Michigan | 49586 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Eyesight Opthalmic Services PA | Portsmouth | New Hampshire | 03801 | — |
| Vitreous Retina Macula Consultants of New York | New York | New York | 10022 | — |
| Charlotte Eye Ear Nose and Throat Associates | Charlotte | North Carolina | 28210 | — |
| Duke University, Duke Eye Center | Durham | North Carolina | 27705 | — |
| Charlotte Eye Ear Nose and Throat Associates | Statesville | North Carolina | 28677 | — |
| Cleveland Clinic Foundation/ Cole Eye Institute | Cleveland | Ohio | 44106 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44122 | — |
| Mid Atlantic | Philadelphia | Pennsylvania | 19006 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Tennessee Retina, PC | Nashville | Tennessee | 37203 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Retina Research Center | Austin | Texas | 78705 | — |
| Retina Consultants of Houston | Houston | Texas | 77030 | — |
| Valley Retina Institute, PA | McAllen | Texas | 75803 | — |
| Retina Specialists | Plano | Texas | 75093 | — |
| Retina Consultants of Houston (The Woodlands) | The Woodlands | Texas | 77384 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02503332, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 6, 2020 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02503332 live on ClinicalTrials.gov.