The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease
Public ClinicalTrials.gov record NCT02505945. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study compares mechanical sphincter augmentation (LINX Reflux Management System) to double-dose proton pump inhibitors (PPIs) for the management of reflux symptoms related to gastroesophageal reflux disease (GERD).
Study identification
- NCT ID
- NCT02505945
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 152 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2015 (Actual)
- Primary completion
- Oct 2017 (Actual)
- Completion
- Aug 2018 (Actual)
- Last update posted
- Jan 7, 2019
2015 – 2018
United States locations
- U.S. sites
- 21
- U.S. states
- 16
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama | Mobile | Alabama | 36617 | — |
| Bapist Health | Heber Springs | Arkansas | — | — |
| University of Southern California | Los Angeles | California | — | — |
| UCSD | San Diego | California | — | — |
| SurgOne Foregut Institute | Englewood | Colorado | 80110 | — |
| Albany Surgical PC | Albany | Georgia | — | — |
| Esophageal Institute of Atlanta, PC. | Atlanta | Georgia | 30309 | — |
| St. Elizabeth Healthcare | Edgewood | Kentucky | 41017 | — |
| Anne Arundel Medical Center | Annapolis | Maryland | — | — |
| Cuyuna Regional Medical Center | Crosby | Minnesota | 56441 | — |
| Jersey Shore University Medical Center | Neptune City | New Jersey | — | — |
| Adirondack Surgical Group, LLC | Saranac Lake | New York | — | — |
| University Hospitals Cleveland Medical Center - Geauga | Cleveland | Ohio | 44106 | — |
| Knox Community Hospital | Mount Vernon | Ohio | — | — |
| The Oregon Clinic | Portland | Oregon | — | — |
| Albert Einstein Healthcare Network | Philadelphia | Pennsylvania | 19141 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Scott and White Memorial Hospital | Round Rock | Texas | 78665 | — |
| Swedish Cancer Institute | Seattle | Washington | — | — |
| Gundersen Lutheran | La Crosse | Wisconsin | — | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02505945, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 7, 2019 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02505945 live on ClinicalTrials.gov.