Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease
Public ClinicalTrials.gov record NCT02507284. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Exploratory Phase II Study to Determine the Tolerability, Safety, and Activity of a Novel Vasopressin 1a Receptor Antagonist (SRX246) in Irritable Subjects With Huntington's Disease (HD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study evaluates the tolerability, safety and activity of SRX246 in the treatment of irritability in patients with Huntington's disease. Two-thirds of all participants will receive SRX246, while the other third will receive a placebo.
Study identification
- NCT ID
- NCT02507284
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 106 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 9, 2016
- Primary completion
- Sep 9, 2018
- Completion
- Dec 20, 2018
- Last update posted
- Jul 19, 2023
2016 – 2018
United States locations
- U.S. sites
- 22
- U.S. states
- 18
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35233 | — |
| UCLA, Neurology Clinic | Los Angeles | California | 90095 | — |
| UC Davis Medical Center, Department of Neurology, CTSC Clinical Research Center | Sacramento | California | 95817 | — |
| University of Colorado Hospital Translational Research Center | Aurora | Colorado | 80045 | — |
| University of Miami, Miller School of Medicine, Jackson Behavioral Health Hospital | Miami | Florida | 33136 | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Northwestern Out-Patient Neurology Clinic | Chicago | Illinois | 60611 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Massachusetts General Hospital | Charlestown | Massachusetts | 02129 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| SUNY Stony Brook Clinical Research Center, Department of Neurology | East Setauket | New York | 11733 | — |
| Columbia University Medical Center, New York Presbyterian Hospital | New York | New York | 10032 | — |
| University of Rochester Medical Center | Rochester | New York | 14618 | — |
| University Medical Arts Building | Cincinnati | Ohio | 45219 | — |
| Ohio State University, Wexner Medical Center, Department of Neurology | Columbus | Ohio | 43221 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| University of Pittsburgh Medical Center, Department of Neurology | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt Clinical Research Center | Nashville | Tennessee | 37232 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| University of Utah, Department of Neurology | Salt Lake City | Utah | 84108 | — |
| University of Virginia Health System, Department of Neurology | Charlottesville | Virginia | 22908 | — |
| Swedish Neuroscience Institute | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02507284, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 19, 2023 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02507284 live on ClinicalTrials.gov.