ClinicalTrials.gov record
PALbociclib CoLlaborative Adjuvant Study
ClinicalTrials.gov ID: NCT02513394
Public ClinicalTrials.gov record NCT02513394. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Early Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a prospective, two arm, international, multicenter, randomized, open-label Phase III study evaluating the addition of 2 years of palbociclib to standard adjuvant endocrine therapy for patients with HR+ / HER2- early breast cancer (EBC). The purpose of the PALLAS study is to determine whether the addition of palbociclib to adjuvant endocrine therapy will improve outcomes over endocrine therapy alone for HR+/HER2- early breast cancer. Assessment of a variety of correlative analysis, including evaluation of the effect of palbociclib in genomically defined tumor subgroups, is planned.
Study identification
- NCT ID
- NCT02513394
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 5,796 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2015 (Type not available)
- Primary completion
- Nov 2020 (Actual)
- Completion
- Dec 2028 (Estimated)
- Last update posted
- Jun 15, 2026
2015 – 2028
United States locations
- U.S. sites
- 192
- U.S. states
- 40
- U.S. cities
- 141
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama Mitchell Cancer Institute | Mobile | Alabama | 36604 | — |
| Southern Cancer Center PC - Providence | Mobile | Alabama | 36608 | — |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | — |
| Providence Alaska Cancer Center | Anchorage | Alaska | 99508 | — |
| Mayo Clinic in Arizona | Phoenix | Arizona | 85054 | — |
| Kaiser Permanente Anaheim Medical Center | Anaheim | California | 92806 | — |
| Kaiser Permanente Baldwin Park Medical Center | Baldwin Park | California | 91706 | — |
| Kaiser Permanente Bellflower Medical Center | Bellflower | California | 90706 | — |
| Kaiser Permanente Fontana Medical Center | Fontana | California | 92335 | — |
| Marin Cancer Care | Greenbrae | California | 94904 | — |
| Marin Cancer Center | Greenbrae | California | 94904 | — |
| Kaiser Permanente Harbor City Medical Center | Harbor City | California | 90710 | — |
| Kaiser Permanente Irvine Medical Center | Irvine | California | 92618 | — |
| UCSD Moores Cancer Center | La Jolla | California | 92093 | — |
| Long Beach Memorial Medical Center - Todd Cancer Institute | Long Beach | California | 90806 | — |
| Kaiser Permanente Sunset Medical Center | Los Angeles | California | 90027 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| Kaiser Permanente Oakland Medical Center | Oakland | California | 94611 | — |
| Palo Alto Medical Foundation Health Care | Palo Alto | California | 94301 | — |
| Kaiser Permanente Panorama City Medical Center | Panorama City | California | 91402 | — |
| Kaiser Permanente Riverside Medical Center | Riverside | California | 92505 | — |
| Kaiser Permanente Roseville Medical Center | Roseville | California | 95661 | — |
| Kaiser Permanente Sacramento Medical Center | Sacramento | California | 95825 | — |
| University of California | San Diego | California | 92093 | — |
| Kaiser Permanente San Diego Medical Center | San Diego | California | 92120 | — |
| Sharp Memorial Hospital | San Diego | California | 92123 | — |
| Kaiser Permanente San Francisco Medical Center | San Francisco | California | 94115 | — |
| UCSF Helen Diller Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| Kaiser Permanente San Jose Medical Center | San Jose | California | 95119 | — |
| Kaiser Permanente San Leandro Medical Center | San Leandro | California | 94577 | — |
| Kaiser Permanente San Marcos Medical Center | San Marcos | California | 92078 | — |
| Kaiser Permanente Santa Clara Medical Center | Santa Clara | California | 95051 | — |
| Kaiser Permanente South San Francisco Medical Center | South San Francisco | California | 94080 | — |
| Stanford Women's Cancer Center | Stanford | California | 94305 | — |
| Kaiser Permanente Vallejo Medical Center | Vallejo | California | 94589 | — |
| Kaiser Permanente Walnut Creek Medical Center | Walnut Creek | California | 94596 | — |
| Kaiser Permanente Cadillac Medical Center | West Los Angeles | California | 90034 | — |
| Kaiser Permanente Woodland Hills Medical Center | Woodland Hills | California | 91367 | — |
| Western States Cancer Research NCORP | Denver | Colorado | 80222 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Memorial Sloan Cancer Center - Hartford Healthcare Center Institute at HOCC | New Britain | Connecticut | 06053 | — |
| Christiana Health System - Christiana Hospital | Newark | Delaware | 19718 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| George Washington University Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| Morton Plant Hospital | Clearwater | Florida | 33756 | — |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | — |
| University of Miami Miller School of Medicine Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | — |
| Advent Health Orlando | Orlando | Florida | 32804 | — |
| Orlando Health Cancer Institute | Orlando | Florida | 32806 | — |
| Phoebe Putney Memorial Hospital | Albany | Georgia | 31701 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Memorial Health University Medical Center | Savannah | Georgia | 317404 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| University of Chicago Cancer Center LAPS | Chicago | Illinois | 60637 | — |
| Cancer Care Specialist of Central Illinois | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| NorthShore University Health System - Evanston Hospital | Evanston | Illinois | 60201 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Joliet Oncology Hematology Associates Limited | Joliet | Illinois | 60435 | — |
| Advocate Lutheran General Hospital | Park Ridge | Illinois | 60068 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| OSF Saint Anthony Medical Center | Rockford | Illinois | 61108 | — |
| Orchard Healthcare Research Inc. | Skokie | Illinois | 60017 | — |
| NorthShore Hematology Oncology-Libertyville | Skokie | Illinois | 60077 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Indiana University - Melvin and Bren Simon Cancer Center LAPS | Indianapolis | Indiana | 46202 | — |
| IU Health Ball Memorial Hospital | Muncie | Indiana | 47303 | — |
| McFarland Clinic PC-William R Bliss Cancer Center | Ames | Iowa | 50010 | — |
| McFarland Clinic, P.C. | Ames | Iowa | 50010 | — |
| Physicians' Clinic of Iowa PC | Cedar Rapids | Iowa | 52403 | — |
| Iowa Oncology Research Assoc | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates - Des Moines | Des Moines | Iowa | 50309 | — |
| Covenant Medical Center | Waterloo | Iowa | 50702 | — |
| University of Kentucky-Markey Cancer Center | Lexington | Kentucky | 40536 | — |
| Norton Cancer Institute - Brownsboro | Louisville | Kentucky | 20202 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| Eastern Maine Medical Center d/b/a Northern Light Cancer Institute | Bangor | Maine | 04401 | — |
| New England Cancer Specialists - Scarborough | Scarborough | Maine | 04074 | — |
| Anne Arundel Medical Center | Annapolis | Maryland | 21401 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| MedStar Good Samaritan Hospital | Baltimore | Maryland | 21218 | — |
| MedStar Franklin Square Medical Center Winberg Cancer Institute | Baltimore | Maryland | 21237 | — |
| Medstar Union Memorial Hospital | Baltimore | Maryland | 21237 | — |
| JHU Sidney Kimmel Comprehensive Cancer Center LAPS | Baltimore | Maryland | 21287 | — |
| Frederick Regional Health System James M Stockman Cancer Institute | Baltimore | Maryland | 21701 | — |
| Maryland Oncology Hematology PA | Bethesda | Maryland | 20817 | — |
| Tidal Health Peninsula Regional | Salisbury | Maryland | 21801 | — |
| Holy Cross Hospital | Silver Spring | Maryland | 20910 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01852 | — |
| Beth Israel Deaconess Hospital - Plymouth Jordan Club Cancer Center | Plymouth | Massachusetts | 02360 | — |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | — |
| Cancer Research Consortium of West Michigan NCORP | Grand Rapids | Michigan | 49503 | — |
| Spectrum Health Butterworth Research Pharmacy | Grand Rapids | Michigan | 49503 | — |
| Trinity Health Michigan | Livonia | Michigan | 48152 | — |
| Essentia Health NCORP | Duluth | Minnesota | 55805 | — |
| Mayo Clinic-Rochester | Rochester | Minnesota | 55902 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Coborn Cancer Center at Saint Cloud Hospital | Saint Cloud | Minnesota | 56303 | — |
| Metro Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | — |
| Metro Minnesota Oncology Research Consortium | Saint Louis Park | Minnesota | 55416 | — |
| St. Luke's Hospital | Kansas City | Missouri | 64111 | — |
| Phelps Country Regional Medical Center | Rolla | Missouri | 65401 | — |
| Cancer Research for the Ozarks NCORP | Springfield | Missouri | 65807 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Nebraska Hematology and Oncology | Lincoln | Nebraska | 68506 | — |
| Southeast Nebraska Cancer Center | Lincoln | Nebraska | 68510 | — |
| Cancer Alliance of Nebraska | Omaha | Nebraska | 68106 | — |
| Missouri Valley Cancer Consortium | Omaha | Nebraska | 68106 | — |
| New Hampshire Oncology-Hematology PA, Concord | Concord | New Hampshire | 03301 | — |
| New Hampshire Oncology-Hematology PA | Hooksett | New Hampshire | 03106 | — |
| Solinsky Center for Cancer Care | Hooksett | New Hampshire | 03106 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Norris Cotton Cancer Center - Nashua | Lebanon | New Hampshire | 03766 | — |
| Englewood Hospital and Medical Center | Englewood | New Jersey | 07631 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Rutgers Cancer Center Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Robert Wood Johnson University Hospital Somerset | Somerville | New Jersey | 08876 | — |
| University of New Mexico Comprehensive Cancer Center | Albuquerque | New Mexico | 87131 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Mary Imogene Bassett Hospital | Cooperstown | New York | 11326 | — |
| Hematology Oncology Associates of Central New York - East Syracuse | East Syracuse | New York | 13057 | — |
| Queens Hospital Center | Jamaica | New York | 11432 | — |
| Northwell Health NCORP | New Hyde Park | New York | 11042 | — |
| Beth Israel Medical Center - New York | New York | New York | 10011 | — |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | — |
| Memorial Sloan Kettering Cancer Center - LAPS | New York | New York | 10065 | — |
| Oneonta FoxCare Center | Oneonta | New York | 13820 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Montefiore Medical Center - Einstein Campus | The Bronx | New York | 10461 | — |
| Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | 28204 | — |
| The Charlotte-Mecklenburg Hospital Authority | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Cone Health Cancer Center | Greensboro | North Carolina | 27403 | — |
| Kinston Medical Specialists, PA | Kinston | North Carolina | 28504 | — |
| First Health of the Carolinas - Moore Regional Hospital | Pinehurst | North Carolina | 28374 | — |
| Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Cleveland Clinic Cancer Center/Hillcrest Hospital | Mayfield Heights | Ohio | 44124 | — |
| Cancer Centers of Southwest Oklahoma Research | Lawton | Oklahoma | 73505 | — |
| Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Hematology & Oncology Associates of Northeastern PA | Dunmore | Pennsylvania | 18512 | — |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17604 | — |
| Hospital of the University of Pennsylvania Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19106 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC MaGee Women's Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| University of Pittsburgh Cancer Institute- Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Reading Hospital/McGlinn Cancer Institute | Wyomissing | Pennsylvania | 19610 | — |
| WellSpan Health York Cancer Center | York | Pennsylvania | 17403 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Women & Infants Hospital of Rhode Island | Providence | Rhode Island | 02905 | — |
| Lexington Medical Center/Lexington Oncology Associates | Columbia | South Carolina | 29169 | — |
| Avera Cancer Institute-Aberdeen | Aberdeen | South Dakota | 57401 | — |
| Monument Health Rapid City Hospital | Rapid City | South Dakota | 57701 | — |
| Rapid City Regional Hospital/Regional Cancer Care Institute | Rapid City | South Dakota | 57701 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37204 | — |
| Nashville General Hospital at Meharry | Nashville | Tennessee | 37208 | — |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Houston | Texas | 77030 | — |
| Houston Methodist Hospital Cancer Center | Houston | Texas | 77030 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Doctors Hospital of Laredo | Laredo | Texas | 78045 | — |
| Huntsman Cancer Institute - University of Utah | Salt Lake City | Utah | 84112 | — |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | — |
| VCU Massey Cancer Center | Richmond | Virginia | 23298 | — |
| CAMC Cancer Center | Charleston | West Virginia | 25304 | — |
| ThedaCare Regional Cancer Center | Appleton | Wisconsin | 54913 | — |
| HSHS Saint Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
| Gunderson Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | — |
| Wheaton Franciscan Healthcare - St. Joseph | Milwaukee | Wisconsin | 53210 | — |
| Columbia St. Mary's Water Tower Medical Commons | Milwaukee | Wisconsin | 53711 | — |
| Wheaton Franciscan Healthcare-All Saints | Racine | Wisconsin | 53405 | — |
| Orchard Healthcare Research Inc. | Waukesha | Wisconsin | 53188 | — |
| UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | 53188 | — |
| Wheaton Franciscan Healthcare - Wauwatosa | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 245 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02513394, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 15, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02513394 live on ClinicalTrials.gov.