ClinicalTrials.gov record
Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DM
ClinicalTrials.gov ID: NCT02526524
Public ClinicalTrials.gov record NCT02526524. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized, Double-Blind, Parallel-Group, Multicenter, Placebo-Controlled, Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release In Subjects With Type 2 Diabetes Mellitus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to compare the glycemic effects of delayed-release metformin (Met DR) to placebo in subjects with type 2 diabetes mellitus (T2DM) over 16 weeks. The study is designed to evaluate several doses of Met DR (600 to 1500 mg once daily in the morning \[qAM\]) compared to placebo. A single-blind reference treatment of 2000 mg metformin immediate-release (Met IR) per day administered as equal divided doses (1000 mg Met IR BID) will also be included.
Study identification
- NCT ID
- NCT02526524
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 571 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 25 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2015
- Primary completion
- Aug 31, 2016
- Completion
- Aug 31, 2016
- Last update posted
- Apr 26, 2018
2015 – 2016
United States locations
- U.S. sites
- 134
- U.S. states
- 33
- U.S. cities
- 110
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group, LLC | Anniston | Alabama | 36207 | — |
| Central Alabama Research | Birmingham | Alabama | 35209 | — |
| Achieve Clinical Research, LLC | Birmingham | Alabama | 35216 | — |
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Terence T. Hart, MD | Tuscumbia | Alabama | 35674 | — |
| Radiant Research - Phoenix | Chandler | Arizona | 85224 | — |
| Arrowhead Health Centers | Glendale | Arizona | 85306 | — |
| Holland Center for Family Health, LTD | Peoria | Arizona | 85381 | — |
| Elite Clinical Studies | Phoenix | Arizona | 85018 | — |
| Thunderbird Internal Medicine - Indian School Rd. | Phoenix | Arizona | 85037 | — |
| Clinical Research Institute of Arizona, LLC | Surprise | Arizona | 85374 | — |
| Summit Clinical Trials Center | Fayetteville | Arkansas | 72703 | — |
| Searcy Medical Center | Searcy | Arkansas | 72143 | — |
| Advanced Metabolic Care & Research Institute (AMCR) | Escondido | California | 92025 | — |
| MD Studies, Inc. | Fountain Valley | California | 92708 | — |
| National Research Institute | Huntington Park | California | 90255 | — |
| Scripps Whittier Diabetes Institute | La Jolla | California | 92037 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| Collaborative Neuroscience Network, LLC | Long Beach | California | 90806 | — |
| National Research Institute | Los Angeles | California | 90057 | — |
| Catalina Research Institute | Montclair | California | 91763 | — |
| SRSD, Inc. dba Synergy San Diego | National City | California | 91950 | — |
| Providence Clinical Research | North Hollywood | California | 91606 | — |
| Pacific Research Partners, LLC | Oakland | California | 94607 | — |
| SDS Clinical Trials, Inc. | Orange | California | 92868 | — |
| Center for Clinical Trials of Sacramento | Sacramento | California | 95823 | — |
| Center for Clinical Trials of Scaramento | Sacramento | California | 95823 | — |
| Superior Research LLC | Sacramento | California | 95825 | — |
| Syrentis Clinical Research (formerly Research Across America) | Santa Ana | California | 92705 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Clinical Trial Investigators | Tustin | California | 92780 | — |
| Infosphere Clinical Research | Van Nuys | California | 91405 | — |
| Colorado Springs Health Partners | Colorado Springs | Colorado | 80906 | — |
| Creekside Endocrine Associates | Denver | Colorado | 80209 | — |
| Meridien Research - Brooksville | Brooksville | Florida | 34601 | — |
| ALL Medical Research, LLC | Cooper City | Florida | 33024 | — |
| Neostart Corporation dba AGA Clinical Trials | Hialeah | Florida | 33012 | — |
| Care Partners Clinical Research | Jacksonville | Florida | 32277 | — |
| Health Awareness, Inc. | Jupiter | Florida | 33458 | — |
| Family Health Care Clinical Studies | Kissimmee | Florida | 34741 | — |
| Clinical Research of Central Florida-Lakeland | Lakeland | Florida | 33810 | — |
| Clinical Pharmacology of Miami, Inc. | Miami | Florida | 33014 | — |
| Tellus Clinical Research, Inc. | Miami | Florida | 33173 | — |
| Internal Research Associates LLC - Breton | Miami | Florida | 33183 | — |
| Clinical Neuroscience Solutions, Inc. Healthcare Orlando | Orlando | Florida | 32801 | — |
| Ormond Medical Arts Pharmaceutical Research Center | Ormond Beach | Florida | 32174 | — |
| Private Practice - Andres Patron, DO | Pembroke Pines | Florida | 33026 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Meridien Reserach - St. Petersburg | St. Petersburg | Florida | 33709 | — |
| Clinical Reserch Trials of Florida | Tampa | Florida | 33607 | — |
| Meridien Research - Tampa | Tampa | Florida | 33634 | — |
| Metabolic Research Institute, Inc. | West Palm Beach | Florida | 33401 | — |
| Biofortis, Inc. | Addison | Illinois | 60101 | — |
| AMR Sakeena Research | Aurora | Illinois | 60506 | — |
| Cedar-Crosse Research Center | Chicago | Illinois | 60607 | — |
| Evanston Premier Healthcare Research LLC | Evanston | Illinois | 60201 | — |
| Buynak Clinical Research, PC | Valparaiso | Indiana | 46383 | — |
| The Iowa Clinic; Cardiovascular Services | West Des Moines | Iowa | 50266 | — |
| Heartland Research Associates, LLC - Augusta | Augusta | Kansas | 67010 | — |
| Cotton-O'Neil Clinical Research Center | Topeka | Kansas | 66606 | — |
| Otrimed | Edgewood | Kentucky | 41017 | — |
| Kentucky Diabetes Endocrinology Center | Lexington | Kentucky | 40503 | — |
| Louisville Metabolic and Atherosclerosis Research Center (L-MARC) | Louisville | Kentucky | 40213 | — |
| Four Rivers Clinical Research | Paducah | Kentucky | 42003 | — |
| Avant Research Associates | Crowley | Louisiana | 70526 | — |
| Centex Studies, Inc. - lake Charles | Lake Charles | Louisiana | 70601 | — |
| Columbia Medical Practice | Columbia | Maryland | 21045 | — |
| Medstar Health Research Institute | Hyattsville | Maryland | 20782 | — |
| MD Medical Research | Oxon Hill | Maryland | 20745 | — |
| Beacon Clinical Research | Quincy | Massachusetts | 02169 | — |
| Radiant Research - Edina | Edina | Minnesota | 55435 | — |
| Planters Clinic | Port Gibson | Mississippi | 39150 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Quality Clinical Research, Inc. | Omaha | Nebraska | 68114 | — |
| Heartland Clinical Research | Omaha | Nebraska | 68134 | — |
| Alliance Against Diabetes | Las Vegas | Nevada | 89101 | — |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | — |
| Palm Medical Research | Las Vegas | Nevada | 89128 | — |
| Ingham Neuroscience Group, LLC | Las Vegas | Nevada | 89146 | — |
| Comprehensive Clinical Research | Berlin | New Jersey | 08009 | — |
| Albuquerque Clinical Trials | Albuquerque | New Mexico | 87102 | — |
| Albuquerque Neuroscience, Inc. | Albuquerque | New Mexico | 87109 | — |
| NY Scientific | Brooklyn | New York | 11235 | — |
| Long Island Gastrointestinal Research Group | Great Neck | New York | 11023 | — |
| Mid-Hudson Medical Research, PLLC | Hopewell Junction | New York | 12533 | — |
| Great Lakes Medical Research | Westfield | New York | 14787 | — |
| PharmQuest | Greensboro | North Carolina | 27408 | — |
| Triad Clinical Trials LLC | Greensboro | North Carolina | 27410 | — |
| PMG Research of Rocky Mount | Rocky Mount | North Carolina | 27804 | — |
| PMG Research of Salisbury, LLC | Salisbury | North Carolina | 28144 | — |
| PMG Research of Wilmington, LLC | Wilmington | North Carolina | 28401 | — |
| Sterling Research Group, Ltd | Cincinnati | Ohio | 45219 | — |
| Metabolic Atherosclerosis Research Center | Cincinnati | Ohio | 45227 | — |
| New Horizons Clinical Research | Cincinnati | Ohio | 45242 | — |
| Urgent Care Specialists, LLC DBA Hometown Urgent Care and Occupational Health | Columbus | Ohio | 43214 | — |
| Prestige Clinical Research | Franklin | Ohio | 45005 | — |
| Hometown Urgent Care and Research - Huber Heights | Huber Heights | Ohio | 45424 | — |
| RAS Health LTD | Marion | Ohio | 43302 | — |
| Summit Reserach Group, LLC | Stow | Ohio | 44224 | — |
| COR Clinical Research, LLC | Oklahoma City | Oklahoma | 73103 | — |
| Willamette Valley Clinical Studies | Eugene | Oregon | 97404 | — |
| Brandywine Clinical Research | Downingtown | Pennsylvania | 19335 | — |
| Medical Research South, LLC | Charleston | South Carolina | 29407 | — |
| Mountain View Clinical Research - Greer | Greer | South Carolina | 29651 | — |
| PMG of Charleston, LLC | Mt. Pleasant | South Carolina | 29464 | — |
| Family Medicine of SayeBrook, LLC | Myrtle Beach | South Carolina | 29588 | — |
| Hillcrest Clinical Research, LLC | Simpsonville | South Carolina | 29681 | — |
| Palmetto Proactive Healthcare, LLC | Spartanburg | South Carolina | 29301 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Palmetto Clinical Research | Summerville | South Carolina | 29485 | — |
| PMG Research of Bristol, LC - State | Bristol | Tennessee | 37620 | — |
| PMG Research of Knoxville | Knoxville | Tennessee | 37912 | — |
| Clinical Neuroscience Solutions, Inc. - Memphis | Memphis | Tennessee | 38119 | — |
| Trinity Clinical Research | Tullahoma | Tennessee | 37388 | — |
| Central Texas Clinical Research | Austin | Texas | 78705 | — |
| Trinity Universal Research Associates, Inc. | Carrollton | Texas | 75007 | — |
| Dallas Diabetes and Endocrine Center | Dallas | Texas | 75230 | — |
| Research Institute of Dallas | Dallas | Texas | 75231 | — |
| Galenos Research | Dallas | Texas | 75251 | — |
| Pioneer Research Solutions, Inc. | Houston | Texas | 77036 | — |
| Centex Studies, Inc. | Houston | Texas | 77058 | — |
| Clinical Trial Network - Houston | Houston | Texas | 77074 | — |
| Juno Research, LLC-Houston | Houston | Texas | 77074 | — |
| Juno Research, LLC-Katy | Katy | Texas | 77450 | — |
| Texas Diabetes Institute Research Center | San Antonio | Texas | 78207 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Victorium Clinical Research | San Antonio | Texas | 78231 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231 | — |
| Southwest Health Associates, P.A. | Sugar Land | Texas | 77478 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| Burke Internal Medicine & Research | Burke | Virginia | 22015 | — |
| Manassas Clinical Research Center | Manassas | Virginia | 20110 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23235 | — |
| Universal Research Group, LLC | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02526524, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 26, 2018 · Synced Sep 2, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02526524 live on ClinicalTrials.gov.