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Completed Phase 2 Interventional Results available

Afrezza Safety and Pharmacokinetics Study in Pediatric Patients

ClinicalTrials.gov ID: NCT02527265

Public ClinicalTrials.gov record NCT02527265. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Open-label, Single-arm, Multiple-dose Safety, Titration, and Pharmacokinetic Trial of Afrezza® in Pediatric Patients Ages 4 to 17 Years With Type 1 Diabetes Mellitus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Primary Objective: -To assess the safety and tolerability of Afrezza in children ages 4 to 17 years with type 1 diabetes mellitus (T1DM). Secondary Objectives: * To assess the ability to titrate the prandial and supplemental doses of Afrezza at each meal. * To assess pharmacokinetics (PK) following a prandial dose of Afrezza in children ages 4 to 17 years with T1DM.

Study identification

NCT ID
NCT02527265
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Mannkind Corporation
Industry
Enrollment
30 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
4 Years to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 27, 2017
Primary completion
Mar 16, 2020
Completion
Jun 24, 2020
Last update posted
Apr 5, 2021

2017 – 2020

United States locations

U.S. sites
13
U.S. states
10
U.S. cities
11
Facility City State ZIP Site status
Children's Hospital Los Angeles Los Angeles California 90027
Barbara Davis Center for Childhood Diabetes Aurora Colorado 80045
Yale University Hospital New Haven Connecticut 06510
University of Florida Gainesville Florida 32610
USF Diabetes Center Tampa Florida 33612
Atlanta Diabetes Associates Atlanta Georgia 30318
Van Meter Pediatric Endocrinology, P.C. Atlanta Georgia 30318
Emory University Children's Center Atlanta Georgia 30322
Indiana University, Riley Hospital for Children Indianapolis Indiana 46202
Barry J. Reiner, MD, LLC Baltimore Maryland 21229
Diabetes, Obesity, Cardiovascular Clinical Specialists (DOCS) Las Vegas Nevada 89113
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Le Bonheur Children's Hospital Memphis Tennessee 38105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02527265, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 5, 2021 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02527265 live on ClinicalTrials.gov.

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