Cobiprostone for the Prevention of Oral Mucositis in Subjects With Head and Neck Cancer Receiving Concurrent Radiation and Chemotherapy
Public ClinicalTrials.gov record NCT02542215. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Placebo-controlled, Double-blinded Study of the Efficacy, Safety, and Pharmacokinetics of Cobiprostone for the Prevention of Severe Oral Mucositis in Subjects With Head and Neck Cancer (HNC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Treatment for head and neck cancer often involves a combination of chemotherapy and radiation. One of the unfortunate consequences of standard care for head and neck cancer is the development of painful mouth sores, known as oral mucositis. This study will evaluate the use of cobiprostone spray to prevent oral mucositis, when given for the duration of radiation and chemotherapy (RT/CT) standard care.
Study identification
- NCT ID
- NCT02542215
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 47 participants
Conditions and interventions
Conditions
Interventions
- Cobiprostone Drug
- Placebo Drug
- Standard Care - Chemotherapy Drug
- Standard Care - Radiation Radiation
Drug · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2015 (Type not available)
- Primary completion
- Jul 2016 (Actual)
- Completion
- Jul 2016 (Actual)
- Last update posted
- Dec 2, 2019
2015 – 2016
United States locations
- U.S. sites
- 76
- U.S. states
- 35
- U.S. cities
- 75
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site | Birmingham | Alabama | 35294 | — |
| Investigational Site | Peoria | Arizona | 85381 | — |
| Investigational Site | Yuma | Arizona | 85364 | — |
| Investigational Site | Little Rock | Arkansas | 72205 | — |
| Investigational Site | Duarte | California | 91010 | — |
| Investigational Site | Fullerton | California | 92835 | — |
| Investigational Site | Los Angeles | California | 90048 | — |
| Investigational Site | Montebello | California | 90640 | — |
| Investigational Site | Oceanside | California | 92056 | — |
| Investigational Site | Redondo Beach | California | 90277 | — |
| Investigational Site | San Francisco | California | 94115 | — |
| Investigational Site | Whittier | California | 90603 | — |
| Investigational Site | Denver | Colorado | 80210 | — |
| Investigational Site | Farmington | Connecticut | 06030 | — |
| Investigational Site | Fort Lauderdale | Florida | 33316 | — |
| Investigational Site | Fort Myers | Florida | 33908 | — |
| Investigational Site | Lakeland | Florida | 33805 | — |
| Investigational Site | Miami Beach | Florida | 33140 | — |
| Investigational Site | Naples | Florida | 34102 | — |
| Investigational Site | Plantation | Florida | 33322 | — |
| Investigational Site | Stuart | Florida | 34994 | — |
| Investigational Site | Winter Haven | Florida | 33880 | — |
| Investigational Site | Boise | Idaho | 83706 | — |
| Investigational Site | Urbana | Illinois | 61801 | — |
| Investigational Site | Fort Wayne | Indiana | 46845 | — |
| Investigational Site | South Bend | Indiana | 46601 | — |
| Investigational Site | Topeka | Kansas | 66606 | — |
| Investigational Site | Ashland | Kentucky | 41101 | — |
| Investigational Site | Baton Rouge | Louisiana | 70809 | — |
| Investigational Site | Metairie | Louisiana | 70006 | — |
| Investigational Site | New Orleans | Louisiana | 70112 | — |
| Investigational Site | Shreveport | Louisiana | 71103 | — |
| Investigational Site | Baltimore | Maryland | 21201 | — |
| Investigational Site | Bethesda | Maryland | 20889 | — |
| Investigational Site | Burlington | Massachusetts | 01805 | — |
| Investigational Site | Ann Arbor | Michigan | 48109 | — |
| Investigational Site | Detroit | Michigan | 48201 | — |
| Investigational Site | East Lansing | Michigan | 48867 | — |
| Investigational Site | Minneapolis | Minnesota | 55417 | — |
| Investigational Site | St Louis | Missouri | 63110 | — |
| Investigational Site | Billings | Montana | 59101 | — |
| Investigational Site | Omaha | Nebraska | 68198 | — |
| Investigational Site | Reno | Nevada | 89502 | — |
| Investigational Site | Egg Harbor | New Jersey | 08234 | — |
| Investigational Site | New Brunswick | New Jersey | 08901 | — |
| Investigational Site | Charlotte | North Carolina | 28203 | — |
| Investigational Site | Gastonia | North Carolina | 28054 | — |
| Investigational Site | Greenville | North Carolina | 27834 | — |
| Investigational Site | Canton | Ohio | 44718 | — |
| Investigational Site | Sylvania | Ohio | 43560 | — |
| Investigational Site | Oklahoma City | Oklahoma | 73104 | — |
| Investigational Site | Coos Bay | Oregon | 97420 | — |
| Investigational Site | Corvallis | Oregon | 97330 | — |
| Investigational Site | Portland | Oregon | 97227 | — |
| Investigational Site | Gettysburg | Pennsylvania | 17325 | — |
| Investigational Site | Hershey | Pennsylvania | 17033 | — |
| Investigational Site | Natrona Heights | Pennsylvania | 15065 | — |
| Investigational Site | Philadelphia | Pennsylvania | 19104 | — |
| Investigational Site | Pittsburgh | Pennsylvania | 15232 | — |
| Investigational Site | State College | Pennsylvania | 16801 | — |
| Investigational Site | Pawtucket | Rhode Island | 02860 | — |
| Investigational Site | Myrtle Beach | South Carolina | 29577 | — |
| Investigational Site | Cookeville | Tennessee | 38501 | — |
| Investigational Site | Austin | Texas | 78701 | — |
| Investigational Site | Fort Sam Houston | Texas | 78234 | — |
| Investigational Site | Galveston | Texas | 77555 | — |
| Investigational Site | Houston | Texas | 77030 | — |
| Investigational Site | Houston | Texas | 77089 | — |
| Investigational Site | Temple | Texas | 76508 | — |
| Investigational Site | Charlottesville | Virginia | 22911 | — |
| Investigational Site | Fort Belvoir | Virginia | 22060 | — |
| Investigational Site | Bellingham | Washington | 98225 | — |
| Investigational Site | Everett | Washington | 98201 | — |
| Investigational Site | Seattle | Washington | 98101 | — |
| Investigational Site | Morgantown | West Virginia | 26506 | — |
| Investigational Site | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02542215, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 2, 2019 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02542215 live on ClinicalTrials.gov.