A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery
Public ClinicalTrials.gov record NCT02542384. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Adaptive Design Study Evaluating the Analgesic Efficacy and Safety of Intravenous CR845 in Patients Undergoing Abdominal Surgery
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study schedule is comprised of a 14-day Screening Period, a treatment period and an observation period. All eligible subjects will be randomized into one of 3 treatment groups (1 of 2 dose levels or matched placebo). Study drug CR845 will be administered intravenously prior to surgery, and at specific time intervals post surgery. Additional rescue pain and anti-nausea medication will be made available. Post surgical changes in pain intensity, nausea and vomiting will be assessed.
Study identification
- NCT ID
- NCT02542384
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 451 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2015 (Type not available)
- Primary completion
- Apr 2018 (Actual)
- Completion
- Jun 2018 (Actual)
- Last update posted
- May 31, 2019
2015 – 2018
United States locations
- U.S. sites
- 23
- U.S. states
- 12
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cara Therapeutics Study Site | Sheffield | Alabama | — | — |
| Cara Therapeutics Study Site | New Haven | Connecticut | — | — |
| Cara Therapeutics Study Site | Bradenton | Florida | 34209 | — |
| Cara Therapeutics Study Site | Gainesville | Florida | — | — |
| Cara Therapeutics Study Site | Maitland | Florida | — | — |
| Cara Therapeutics Study Site | Miami Gardens | Florida | — | — |
| Cara Therapeutics Study Site | Pensacola | Florida | 32503 | — |
| Cara Therapeutics Study Site | St. Petersburg | Florida | 33713 | — |
| Cara Therapeutics Study Site | Chicago | Illinois | — | — |
| Cara Therapeutics Study Site | Boston | Massachusetts | — | — |
| Cara Therapeutics Study Site | Camden | New Jersey | 08103 | — |
| Cara Therapeutics Study Site | Neptune City | New Jersey | — | — |
| Cara Therapeutics Study Site | Durham | North Carolina | 27710 | — |
| Cara Therapeutics Study Site | Cleveland | Ohio | — | — |
| Cara Therapeutics Study Site | Columbus | Ohio | — | — |
| Cara Therapeutics Study Site | Pittsburgh | Pennsylvania | — | — |
| Cara Therapeutics Study Site | Chattanooga | Tennessee | — | — |
| Cara Therapeutics Study Site | Bellaire | Texas | — | — |
| Cara Therapeutics Study Site | Fort Worth | Texas | — | — |
| Cara Therapeutics Study Site | Houston | Texas | — | — |
| Cara Therapeutics Study Site | Plano | Texas | — | — |
| Cara Therapeutics Study Site | San Antonio | Texas | — | — |
| Cara Therapeutics Study Site | Salt Lake City | Utah | 84124 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02542384, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 31, 2019 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02542384 live on ClinicalTrials.gov.