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Completed Phase 2Phase 3 Interventional

A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery

ClinicalTrials.gov ID: NCT02542384

Public ClinicalTrials.gov record NCT02542384. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 4:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Adaptive Design Study Evaluating the Analgesic Efficacy and Safety of Intravenous CR845 in Patients Undergoing Abdominal Surgery

Study identification

NCT ID
NCT02542384
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Cara Therapeutics, Inc.
Industry
Enrollment
451 participants

Conditions and interventions

Interventions

  • CR845 IV 1 mcg/kg Drug
  • CR845 IV 0.5 mcg/kg Drug
  • Placebo IV Drug

Drug

Eligibility (public fields only)

Age range
21 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2015
Primary completion
Mar 31, 2018
Completion
May 31, 2018
Last update posted
May 30, 2019

2015 – 2018

United States locations

U.S. sites
23
U.S. states
12
U.S. cities
23
Facility City State ZIP Site status
Cara Therapeutics Study Site Sheffield Alabama
Cara Therapeutics Study Site New Haven Connecticut
Cara Therapeutics Study Site Bradenton Florida 34209
Cara Therapeutics Study Site Gainesville Florida
Cara Therapeutics Study Site Maitland Florida
Cara Therapeutics Study Site Miami Gardens Florida
Cara Therapeutics Study Site Pensacola Florida 32503
Cara Therapeutics Study Site St. Petersburg Florida 33713
Cara Therapeutics Study Site Chicago Illinois
Cara Therapeutics Study Site Boston Massachusetts
Cara Therapeutics Study Site Camden New Jersey 08103
Cara Therapeutics Study Site Neptune City New Jersey
Cara Therapeutics Study Site Durham North Carolina 27710
Cara Therapeutics Study Site Cleveland Ohio
Cara Therapeutics Study Site Columbus Ohio
Cara Therapeutics Study Site Pittsburgh Pennsylvania
Cara Therapeutics Study Site Chattanooga Tennessee
Cara Therapeutics Study Site Bellaire Texas
Cara Therapeutics Study Site Fort Worth Texas
Cara Therapeutics Study Site Houston Texas
Cara Therapeutics Study Site Plano Texas
Cara Therapeutics Study Site San Antonio Texas
Cara Therapeutics Study Site Salt Lake City Utah 84124

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02542384, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 30, 2019 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02542384 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →