Open-Label Phase 3 Study to Examine the Long-Term Safety, Tolerability and Efficacy of APL-130277 for the Acute Treatment of "OFF" Episodes in Patients With Parkinson's Disease
Public ClinicalTrials.gov record NCT02542696. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Phase 3 Study Examining the Long-Term Safety, Tolerability and Efficacy of APL-130277 in Levodopa Responsive Patients With Parkinson's Disease Complicated by Motor Fluctuations ("OFF" Episodes)
Study identification
- NCT ID
- NCT02542696
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Sumitomo Pharma America, Inc.
- Industry
- Enrollment
- 496 participants
Conditions and interventions
Conditions
Interventions
- APL-130277 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 30, 2015
- Primary completion
- Nov 7, 2022
- Completion
- Nov 7, 2022
- Last update posted
- Nov 21, 2023
2015 – 2022
United States locations
- U.S. sites
- 48
- U.S. states
- 24
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham | Birmingham | Alabama | 35233 | — |
| Muhammed Ali Parkinson and Movement Disorder Center/Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Movement Disorders Center of Arizona | Scottsdale | Arizona | 85258 | — |
| Clinical Trials, Inc. | Little Rock | Arkansas | 72205 | — |
| The Parkinson's and Movement Disorder Institute | Fountain Valley | California | 92708 | — |
| UC Irvine Health Gottschalk Medical Plaza | Irvine | California | 92697 | — |
| Keck Medical Center at USC | Los Angeles | California | 90033 | — |
| University of Colorado School of Medicine | Aurora | Colorado | 80045 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Parkinsons Disease and Movement Disorders Center | Boca Raton | Florida | 33486 | — |
| University of Miami, Miller School of Medicine | Miami | Florida | 33136 | — |
| Parkinson's Disease Treatment Center of Southwest Florida | Port Charlotte | Florida | 33980 | — |
| Suncoast Neuroscience Associates Inc. | St. Petersburg | Florida | 33713 | — |
| USF Parkinson's Disease and Movement Disorder Center | Tampa | Florida | 33613 | — |
| Emory University Department of Neurology | Atlanta | Georgia | 30329 | — |
| GRU Movement Disorders | Augusta | Georgia | 30912 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| NorthShore Neurological Institute B043D | Glenview | Illinois | 60026 | — |
| Central DuPage Hospital - Neurodegenerative Clinic - Movement Disorders Center | Winfield | Illinois | 60190 | — |
| University of Iowa Dept. of Neurology | Iowa City | Iowa | 52242 | — |
| Kansas University Medical Center-Department of Neurology | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Michigan State University - Dept. of Neurology | East Lansing | Michigan | 48824 | — |
| QUEST Research Institute | Farmington Hills | Michigan | 48334 | — |
| Henry Ford Hospital | West Bloomfield | Michigan | 48322 | — |
| Park Nicolet Institute - Stuthers Parkinson's Center | Golden Valley | Minnesota | 55427 | — |
| SUNY Downstate Medical Center, Department of Neurology | Brooklyn | New York | 11203 | — |
| Bendheim Parkinson's and Movement Disorder Center (Mount Sinai Medical Center) | New York | New York | 10029 | — |
| Columbia University Medical Center - Neurological Institute, Movement Disorders | New York | New York | 10032 | — |
| Duke University - Movement Disorders Clinic | Durham | North Carolina | 27705 | — |
| Raleigh Neurology Associates, P.A. | Raleigh | North Carolina | 27607 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| UT Gardner-McMaster Parkinson's Center | Toledo | Ohio | 43614 | — |
| The Movement Disorder Clinic of Oklahoma | Tulsa | Oklahoma | 74136 | — |
| Jefferson University Hospital Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Houston Methodist Neurological Institute | Houston | Texas | 77030 | — |
| East Texas Medical Center | Tyler | Texas | 75701 | — |
| University of Virginia Adult Neurology | Charlottesville | Virginia | 322903 | — |
| Sentara Neuroscience Institute | Virginia Beach | Virginia | 23456 | — |
| Evergreen Health | Kirkland | Washington | 98034 | — |
| Swedish Neuroscience Research | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02542696, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 21, 2023 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02542696 live on ClinicalTrials.gov.