A Study to Evaluate the Effect of Dapagliflozin With and Without Saxagliptin on Albuminuria, and to Investigate the Effect of Dapagliflozin and Saxagliptin on HbA1c in Patients With Type 2 Diabetes and CKD
Public ClinicalTrials.gov record NCT02547935. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Exploratory Phase II/III, Randomized, Double-blind, Placebo Controlled, Parallel Design Study to Evaluate the Efficacy, Safety and Pharmacodynamics of Dapagliflozin and Dapagliflozin in Combination With Saxagliptin in CKD Patients With Type 2 Diabetes Mellitus and Albuminuria Treated With ACEi or ARB
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this clinical research study is to determine whether dapagliflozin alone or in combination with saxagliptin can decrease albuminuria and improve glycemic control in patients with Type 2 diabetes, albuminuria and renal impairment (CKD). The study is planned to randomize a total of 450 patients (150 patients per treatment arm)
Study identification
- NCT ID
- NCT02547935
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 459 participants
Conditions and interventions
Interventions
- Dapagliflozin 10 mg Drug
- Saxagliptin 2.5 mg Drug
- Matching Placebo for Dapagliflozin 10 mg and Saxagliptin 2.5mg Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 130 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 21, 2015 (Actual)
- Primary completion
- May 18, 2018 (Actual)
- Completion
- May 18, 2018 (Actual)
- Last update posted
- Aug 21, 2019
2015 – 2018
United States locations
- U.S. sites
- 37
- U.S. states
- 16
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Peoria | Arizona | 85381 | — |
| Research Site | Chula Vista | California | 91910 | — |
| Research Site | Concord | California | 94520 | — |
| Research Site | El Centro | California | 92243 | — |
| Research Site | La Mesa | California | 92123 | — |
| Research Site | Long Beach | California | 90807 | — |
| Research Site | Los Gatos | California | 95032 | — |
| Research Site | North Hollywood | California | 91606 | — |
| Research Site | Riverside | California | 92505 | — |
| Research Site | San Diego | California | 92111 | — |
| Research Site | San Dimas | California | 91773 | — |
| Research Site | Hollywood | Florida | 33024 | — |
| Research Site | Miami | Florida | 33126 | — |
| Research Site | New Port Richey | Florida | 34652 | — |
| Research Site | Palm Harbor | Florida | 34684 | — |
| Research Site | Pompano Beach | Florida | 33060 | — |
| Research Site | Augusta | Georgia | 30909 | — |
| Research Site | Meridian | Idaho | 83642 | — |
| Research Site | Chicago | Illinois | 60643 | — |
| Research Site | Bangor | Maine | 04401 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | Las Vegas | Nevada | 89148 | — |
| Research Site | Springfield Gardens | New York | 11413 | — |
| Research Site | The Bronx | New York | 10459 | — |
| Research Site | Greensboro | North Carolina | 27408 | — |
| Research Site | Morehead City | North Carolina | 28557 | — |
| Research Site | Rocky Mount | North Carolina | 27804 | — |
| Research Site | Philadelphia | Pennsylvania | 19107 | — |
| Research Site | Greenville | South Carolina | 29605 | — |
| Research Site | Brownsville | Texas | 78520 | — |
| Research Site | Cypress | Texas | 77429 | — |
| Research Site | Houston | Texas | 77004 | — |
| Research Site | San Antonio | Texas | 78215 | — |
| Research Site | Sugar Land | Texas | 77479 | — |
| Research Site | Salt Lake City | Utah | 84124 | — |
| Research Site | Burke | Virginia | 22015 | — |
| Research Site | Richmond | Virginia | 23219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 75 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02547935, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 21, 2019 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02547935 live on ClinicalTrials.gov.