Hepatocellular Carcinoma Study Comparing Vaccinia Virus Based Immunotherapy Plus Sorafenib vs Sorafenib Alone
Public ClinicalTrials.gov record NCT02562755. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Open-Label Study Comparing Pexa Vec (Vaccinia GM CSF / Thymidine Kinase-Deactivated Virus) Followed by Sorafenib Versus Sorafenib in Patients With Advanced Hepatocellular Carcinoma (HCC) Without Prior Systemic Therapy
Study identification
- NCT ID
- NCT02562755
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- SillaJen, Inc.
- Industry
- Enrollment
- 459 participants
Conditions and interventions
Conditions
Interventions
- Pexastimogene Devacirepvec (Pexa Vec) Biological
- Sorafenib Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2015
- Primary completion
- Jun 30, 2020
- Completion
- Jun 30, 2020
- Last update posted
- Jun 7, 2026
2015 – 2020
United States locations
- U.S. sites
- 23
- U.S. states
- 19
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35294 | — |
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| UC Irvine Medical Center | Orange | California | 92868 | — |
| Stanford University School of Medicine | Palo Alto | California | 94304 | — |
| University of Florida Shands Hospital | Gainesville | Florida | 32608 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| University of Kansas Cancer Center | Kansas City | Kansas | 66205 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Mercy Medical Center, Inc. | Baltimore | Maryland | 21202 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Billings Clinic | Billings | Montana | 59101 | — |
| Morristown Medical Center | Morristown | New Jersey | 07960 | — |
| St. Joseph's Hospital | Paterson | New Jersey | 07503 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Hospital of The University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Benaroya Research Institute at Virginia Mason Hospital | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 119 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02562755, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2026 · Synced Jul 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02562755 live on ClinicalTrials.gov.