ClinicalTrials.gov record
An Open-label, Long-term, Safety Study of Lasmiditan for the Acute Treatment of Migraine
ClinicalTrials.gov ID: NCT02565186
Public ClinicalTrials.gov record NCT02565186. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label, LonG-term, Safety Study of LAsmiDItan (100 mg and 200 mg) in the Acute Treatment Of MigRaine (GLADIATOR)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a prospective, randomized, open-label study in subjects with migraine who have completed the Phase 3 studies, COL MIG 301/LAHJ (NCT02439320) or COL MIG-302/LAHK (NCT02605174) or for a subset of lasmiditan-naïve subjects with migraine. The study is designed to evaluate the safety and tolerability of long-term intermittent use of lasmiditan 100 mg and of lasmiditan 200 mg, as the first dose and as a second dose, for the acute treatment of migraine. Long term efficacy will also be evaluated.
Study identification
- NCT ID
- NCT02565186
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,171 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 7, 2015 (Actual)
- Primary completion
- Aug 20, 2019 (Actual)
- Completion
- Aug 20, 2019 (Actual)
- Last update posted
- Aug 25, 2020
2015 – 2019
United States locations
- U.S. sites
- 182
- U.S. states
- 36
- U.S. cities
- 135
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southview Medical Group | Birmingham | Alabama | 35205 | — |
| Simon Williamson Clinic | Birmingham | Alabama | 35211 | — |
| Achieve Clinical Research, LLC | Birmingham | Alabama | 35216 | — |
| Alabama Clinical Therapeutics | Birmingham | Alabama | 35235 | — |
| Medical Affiliated Research Center | Huntsville | Alabama | 35801 | — |
| East Valley Family Physicians, PLC | Chandler | Arizona | 85224 | — |
| Radiant Research | Chandler | Arizona | 85224 | — |
| Warner Family Practice | Chandler | Arizona | 85224 | — |
| Fountain Hills Family Practice, P.C. | Fountain Hills | Arizona | 85268 | — |
| Neurological Physicians of Arizona Inc | Gilbert | Arizona | 85234 | — |
| Thunderbird Internal Medicine | Glendale | Arizona | 85306 | — |
| Thomas C. Lenzmeier, M.D., P.C | Glendale | Arizona | 85308 | — |
| Central Arizona Medical Associates, PC | Mesa | Arizona | 85206 | — |
| Desert Clinical Research | Mesa | Arizona | 85213 | — |
| 21st Century Neurology | Phoenix | Arizona | 85004 | — |
| Family Practice Specialists Ltd | Phoenix | Arizona | 85018 | — |
| Central Phoenix Med Clinic LLC | Phoenix | Arizona | 85020 | — |
| Thunderbird Internal Medicine | Phoenix | Arizona | 85037 | — |
| Tatum Highlands Medical Associates, PLLC | Phoenix | Arizona | 85050 | — |
| Radiant Research | Scottsdale | Arizona | 85251 | — |
| Arizona Community Physicians | Tucson | Arizona | 85712 | — |
| Orange Grove Family Practice | Tucson | Arizona | 85741 | — |
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| Radiant Research | Carlsbad | California | 92008 | — |
| The Research Center of Southern California | Carlsbad | California | 92011 | — |
| eStudySite | Chula Vista | California | 91911 | — |
| Allied Clinical Research | Gold River | California | 95670 | — |
| Pharmacology Research Institute | Los Alamitos | California | 90720 | — |
| Pharmacology Research Institute | Newport Beach | California | 92660 | — |
| Pacific Research Partners, LLC | Oakland | California | 94607 | — |
| Desert Valley Research | Rancho Mirage | California | 92270 | — |
| Northern California Clinical Research Center | Redding | California | 96001 | — |
| Anderson Clinical Research | Redlands | California | 92374 | — |
| California Research Foundation | San Diego | California | 92103-6204 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Neurological Research Institute | Santa Monica | California | 90404 | — |
| Radiant Research | Santa Rosa | California | 95405 | — |
| Schuster Medical Research Institute | Sherman Oaks | California | 91403 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Radiant Research - Vista CA | Vista | California | 92083 | — |
| Diablo Clinical Research | Walnut Creek | California | 94598 | — |
| Mile High Primary Care | Aurora | Colorado | 80014 | — |
| Alpine Clinical Research Center | Boulder | Colorado | 80301 | — |
| Colorado Springs Family Practice | Colorado Springs | Colorado | 80909 | — |
| Colorado Springs Health Partners, PC | Colorado Springs | Colorado | 80922 | — |
| Clinical Trials of the Rockies | Denver | Colorado | 80209 | — |
| Chase Medical Research, LLC | Hamden | Connecticut | 06517 | — |
| Comprehensive Psychiatric Care, PC | Norwich | Connecticut | 06360 | — |
| Nova Clinical Research, LLC | Bradenton | Florida | 34209 | — |
| PAB Clinical Research | Brandon | Florida | 33511 | — |
| Meridien Research | Brooksville | Florida | 34601 | — |
| Avail Clinical Research LLC | DeLand | Florida | 32720 | — |
| Clinical Research West Coast | Fort Myers | Florida | 33901 | — |
| MD Clinical | Hallandale | Florida | 33009 | — |
| Indago Research & Health Center, Inc. | Hialeah | Florida | 33012 | — |
| Infinity Clinical Research, LLC | Hollywood | Florida | 33021 | — |
| Clinical Neuroscience Solutions Inc | Jacksonville | Florida | 32256 | — |
| Meridien Research | Maitland | Florida | 32751 | — |
| Pharmax Research Clinic | Miami | Florida | 33126 | — |
| Prestige Clinical Research | Miami | Florida | 33133 | — |
| Suncoast Research Group, LLC | Miami | Florida | 33135 | — |
| Florida Medical Center and Research, Inc. | Miami | Florida | 33142 | — |
| The Core Research Associates | Miami | Florida | 33172 | — |
| Veritas Research Corp | Miami Lakes | Florida | 33014 | — |
| Ocean Blue Medical Research Center, Inc. | Miami Springs | Florida | 33166 | — |
| Harmony Medical Research Institute, Inc | North Miami Beach | Florida | 33162 | — |
| Clinical Neuroscience Solutions Inc | Orlando | Florida | 32801 | — |
| Compass Research | Orlando | Florida | 32806 | — |
| Radiant Research | Pinellas Park | Florida | 33781 | — |
| Clinical Research Center, LLC | Royal Palm Beach | Florida | 33411 | — |
| Meridien Research | St. Petersburg | Florida | 33709 | — |
| Infinity Clinical Research, LLC | Sunrise | Florida | 33351 | — |
| Meridien Research | Tampa | Florida | 33634 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Radiant Research | Atlanta | Georgia | 30328 | — |
| Atlanta Center of Medical Research | Atlanta | Georgia | 30331 | — |
| Columbus Regional Research Institute | Columbus | Georgia | 31904 | — |
| Urban Family Practice Associates, PC | Marietta | Georgia | 30067 | — |
| Harbin Clinic | Rome | Georgia | 30165 | — |
| Meridian Clinical Research | Savannah | Georgia | 31406 | — |
| Pinnacle Trials, Inc | Stockbridge | Georgia | 30281 | — |
| Georgia Neurology & Sleep Medicine Associates | Suwanee | Georgia | 30024 | — |
| Northwest Clinical Trials | Boise | Idaho | 83704 | — |
| Advanced Clinical Research LLC | Meridian | Idaho | 83642 | — |
| Radiant Research | Chicago | Illinois | 60602 | — |
| Michigan Avenue Internists | Chicago | Illinois | 60604 | — |
| Medical and Procedural Specialists of Illinois | Chicago | Illinois | 60631 | — |
| Evanston Premier Healthcare Research, LLC. | Evanston | Illinois | 60201 | — |
| Clinical Investigation Specialists Inc | Gurnee | Illinois | 60031 | — |
| Synexus/Clinical Research Advantage | Evansville | Indiana | 47714 | — |
| Synexus - US | Evansville | Indiana | 47715 | — |
| Goldpoint Clinical Research LLC | Indianapolis | Indiana | 46260 | — |
| Radiant Research, Inc. | Council Bluffs | Iowa | 51503 | — |
| Heartland Research Associates | Augusta | Kansas | 67010 | — |
| Heartland Research Associates | Newton | Kansas | 67114 | — |
| Continuum Health Care | Overland Park | Kansas | 66210 | — |
| Heartland Research Associates | Wichita | Kansas | 67205 | — |
| Heartland Research Associates | Wichita | Kansas | 67207 | — |
| Central Kentucky Research Associates Inc | Lexington | Kentucky | 40509 | — |
| Associates in Neurology, PSC | Lexington | Kentucky | 40513 | — |
| Research Integrity, LLC | Owensboro | Kentucky | 42303 | — |
| New Orleans Center for Clinical Research | New Orleans | Louisiana | 70119 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| Beacon Clinical Research, LLC | Quincy | Massachusetts | 02169 | — |
| Michigan Head, Pain and Neurological Institute | Ann Arbor | Michigan | 48104 | — |
| Radiant Research | Edina | Minnesota | 55345 | — |
| Clinical Research Institute | Plymouth | Minnesota | 55441 | — |
| West Florissant Internists | Bridgeton | Missouri | 63044 | — |
| The Center For Pharmaceutical Research | Kansas City | Missouri | 64114 | — |
| Radiant Research | St Louis | Missouri | 63141 | — |
| Skyline Medical Center | Elkhorn | Nebraska | 68022 | — |
| Prairie Fields Family Medicine, PC | Fremont | Nebraska | 68025 | — |
| Quality Clinical Research, Inc. | Omaha | Nebraska | 68114 | — |
| Meridian Clinical Research | Omaha | Nebraska | 68134 | — |
| Diagnostic Center of Medicine | Henderson | Nevada | 89014 | — |
| Rita B. Chuang, MD LLC | Henderson | Nevada | 89052 | — |
| Nevada Family Care | Henderson | Nevada | 89074 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89113 | — |
| Diagnostic Center of Medicine | Las Vegas | Nevada | 89117 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| Bio Behavioral Health | Toms River | New Jersey | 08755 | — |
| Albuquerque Clinical Trials | Albuquerque | New Mexico | 87102 | — |
| Regional Clinical Research | Endwell | New York | 13760 | — |
| CNS Research Science, Inc. | Jamaica | New York | 11432 | — |
| Rochester Clinical Research, Inc. | Rochester | New York | 14609 | — |
| Asheville Neurology Specialists, PA | Asheville | North Carolina | 28806 | — |
| PMG Research of Cary, LLC | Cary | North Carolina | 27518 | — |
| Radiant Research | Akron | Ohio | 44311 | — |
| Synexus - US | Cincinnati | Ohio | 45236 | — |
| IVA Research | Cincinnati | Ohio | 45245 | — |
| Rapid Medical Research Inc | Cleveland | Ohio | 44122 | — |
| Synexus - US | Columbus | Ohio | 43212 | — |
| Oklahoma City Clinic | Edmond | Oklahoma | 73034 | — |
| Oklahoma City Clinic | Midwest City | Oklahoma | 73110 | — |
| Lynn Institute of Norman | Norman | Oklahoma | 73069 | — |
| Oklahoma City Clinic | Oklahoma City | Oklahoma | 73104 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Sunstone Medical Research, LLC | Medford | Oregon | 97504 | — |
| Summit Research Network Inc | Portland | Oregon | 97210 | — |
| Oregon Center for Clinical Investigations, Inc. | Portland | Oregon | 97214 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Partners in Clinical Research, LLC | Cumberland | Rhode Island | 02864 | — |
| Lincoln Research | Lincoln | Rhode Island | 02865 | — |
| West Bay Clinical Research | Warwick | Rhode Island | 2886 | — |
| Primary Care Associates | Anderson | South Carolina | 29621 | — |
| Radiant Research | Anderson | South Carolina | 29621 | — |
| Clinical Trials of South Carolina | Charleston | South Carolina | 29406 | — |
| Medical Research South | Charleston | South Carolina | 29407 | — |
| Radiant Research | Greer | South Carolina | 29650 | — |
| Mountain View Clinical Research, Inc. | Greer | South Carolina | 29651 | — |
| Coastal Carolina Research Center, Inc. | Mt. Pleasant | South Carolina | 29464 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| ClinSearch | Chattanooga | Tennessee | 37421 | — |
| Holston Medical Group Clinical Research | Kingsport | Tennessee | 37660 | — |
| New Orleans Center for Clinical Research | Knoxville | Tennessee | 37920 | — |
| Clinical Neuroscience Solutions Inc | Memphis | Tennessee | 38119 | — |
| Nashville Neuroscience Group, Inc. | Nashville | Tennessee | 37203 | — |
| Central Texas Clinical Research, LLC | Austin | Texas | 78705 | — |
| FutureSearch Trials | Austin | Texas | 78731 | — |
| ACRC Trials | Austin | Texas | 78735 | — |
| Tekton Research, Inc | Austin | Texas | 78745 | — |
| ACRC Trials | Carrollton | Texas | 75010 | — |
| FutureSearch Trials | Dallas | Texas | 75231 | — |
| Radiant Research - Dallas North | Dallas | Texas | 75231 | — |
| Protenium Clinical Research | Hurst | Texas | 76054 | — |
| ACRC Trials | Plano | Texas | 75024 | — |
| Doctors of Internal Medicine | Plano | Texas | 75093 | — |
| Plano Internal Medicine Associates | Plano | Texas | 75093 | — |
| Clinical Trials of Texas, Inc. | San Antonio | Texas | 78229 | — |
| Radiant Research - San Antonio | San Antonio | Texas | 78229 | — |
| MacGregor Medical Center | San Antonio | Texas | 78240 | — |
| Ericksen Research and Development | Clinton | Utah | 84015 | — |
| Radiant Research | Murray | Utah | 84123 | — |
| Jean Brown Research | Salt Lake City | Utah | 84096 | — |
| Wasatch Clinical Research, LLC | Salt Lake City | Utah | 84107 | — |
| J. Lewis Research, Inc. | Salt Lake City | Utah | 84109 | — |
| J. Lewis Research, Inc. | Salt Lake City | Utah | 84121 | — |
| Jordan River Family Medicine | South Jordan | Utah | 84095 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23220 | — |
| Multicare Health System | Tacoma | Washington | 98405 | — |
| Clinical Investigation Specialists Inc | Kenosha | Wisconsin | 53144 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02565186, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 25, 2020 · Synced Nov 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02565186 live on ClinicalTrials.gov.