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Active, not recruiting Phase 1 Interventional

Immunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK Cells

ClinicalTrials.gov ID: NCT02573896

Public ClinicalTrials.gov record NCT02573896. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 4, 2026, 9:39 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I Dose Escalation Study of Autologous Expanded Natural Killer (NK) Cells for Immunotherapy of Relapsed Refractory Neuroblastoma With Dinutuximab +/- Lenalidomide

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This NANT trial will determine the maximum tolerated dose (MTD) of autologous expanded natural killer (NK) cells when combined with standard dosing of dinutuximab and will assess the feasibility of adding lenalidomide at the recommended Phase II dose of the expanded NK cells with dinutuximab, for treatment of children with refractory or recurrent neuroblastoma.

Study identification

NCT ID
NCT02573896
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1
Enrollment
13 participants

Conditions and interventions

Conditions

Interventions

Drug · Biological

Eligibility (public fields only)

Age range
Up to 30 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 14, 2019 (Actual)
Primary completion
Dec 2026 (Estimated)
Completion
Dec 2026 (Estimated)
Last update posted
Mar 23, 2026

2019 – 2026

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
11
Facility City State ZIP Site status
Children's Hospital Los Angeles Los Angeles California 90027-0700 —
UCSF Helen Diller Family Comprehensive Cancer Center San Francisco California 94115 —
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus Atlanta Georgia 30322 —
University of Chicago Comer Children's Hospital Chicago Illinois 60637 —
Childrens Hospital Boston, Dana-Farber Cancer Institute. Boston Massachusetts 02115 —
C.S Mott Children's Hospital Ann Arbor Michigan 48109 —
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229-3039 —
Nationwide Children's Hospital Columbus Ohio 43205 —
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104-4318 —
Cook Children's Healthcare System Fort Worth Texas 76104 —
Seattle Children's Hospital Seattle Washington 98105 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02573896, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 23, 2026 · Synced Nov 4, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02573896 live on ClinicalTrials.gov.

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