ClinicalTrials.gov record
A Study of Nivolumab in Advanced Non-Small Cell Lung Cancer (NSCLC)
ClinicalTrials.gov ID: NCT02574078
Public ClinicalTrials.gov record NCT02574078. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Master Protocol of Phase 1/2 Studies of Nivolumab in Advanced NSCLC Using Nivolumab as Maintenance After Induction Chemotherapy or as First-line Treatment Alone or in Combination With Standard of Care Therapies (CheckMate 370: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 370)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether nivolumab monotherapy or in combination with Standard of care (SOC) therapies will provide clinical benefit (i.e., PFS, OS, and DOR) without unacceptable toxicity in advanced Non-Small Cell Lung Cancer patients.
Study identification
- NCT ID
- NCT02574078
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 341 participants
Conditions and interventions
Conditions
Interventions
- Nivolumab Drug
- Bevacizumab Drug
- Pemetrexed Drug
- Best Supportive Care Other
- nab-Paclitaxel Drug
- Paclitaxel Drug
- Docetaxel Drug
- Gemcitabine Drug
- Erlotinib Drug
- Crizotinib Drug
- Carboplatin Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 23, 2015 (Actual)
- Primary completion
- Apr 15, 2020 (Actual)
- Completion
- Apr 15, 2020 (Actual)
- Last update posted
- May 6, 2021
2015 – 2020
United States locations
- U.S. sites
- 133
- U.S. states
- 37
- U.S. cities
- 120
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Oncology | Birmingham | Alabama | 35205 | — |
| Southern Cancer Center Pc | Mobile | Alabama | 36608 | — |
| Arizona Oncology Assoc, Pc-Hal | Glendale | Arizona | 85308 | — |
| Northern Arizona Hematology & Oncology Associates | Sedona | Arizona | 86336 | — |
| Arizona Oncol Assoc Dba (Hem Onc Physicians&Extenders) Hope | Tucson | Arizona | 85704 | — |
| Arizona Clinical Research Center, Inc. | Tucson | Arizona | 85715 | — |
| Comprehensive Blood And Cancer Center | Bakersfield | California | 93309 | — |
| St. Joseph Heritage Medical Group | Fullerton | California | 92835 | — |
| Scripps Cancer Center | La Jolla | California | 92037 | — |
| UCLA Hematology/Oncology Clinic | Los Angeles | California | 90095 | — |
| Coastal Integrative Cancer Care | San Luis Obispo | California | 93401 | — |
| Central Coast Med Oncology | Santa Maria | California | 93454 | — |
| Local Institution | Solvang | California | 93463 | — |
| St. Mary's Hospital Regional Cancer Center | Grand Junction | Colorado | 81501 | — |
| Rocky Mountain Cancer Centers | Lakewood | Colorado | 80228 | — |
| Eastern Ct Hem Onc Assoc | Norwich | Connecticut | 06360 | — |
| Stamford Hospital | Stamford | Connecticut | 06904 | — |
| Va Ct Healthcare System | West Haven | Connecticut | 06516 | — |
| Florida Cancer Specialists S. | Fort Myers | Florida | 33901 | — |
| University of Florida at Shands | Gainesville | Florida | 32610 | — |
| Memorial Cancer Institute | Hollywood | Florida | 33201 | — |
| Baptist Health Medical Group Oncology | Miami | Florida | 33176 | — |
| Ocala Oncology Center | Ocala | Florida | 34471 | — |
| Hematology Oncology Associates Of The Treasure Coast | Port Saint Lucie | Florida | 34952 | — |
| Florida Cancer Specialists | St. Petersburg | Florida | 33705 | — |
| Tallahassee Memorial Cancer Center | Tallahassee | Florida | 32308 | — |
| Florida Cancer Affiliates | Trinity | Florida | 34655 | — |
| University Cancer Blood Ctr | Athens | Georgia | 30607 | — |
| Cancer Treatment Centers Of America | Newnan | Georgia | 30265 | — |
| Summit Cancer Care | Savannah | Georgia | 31405 | — |
| Lewis Hall Singletary Oncology Center | Thomasville | Georgia | 31792 | — |
| Illinois Cancer Specialists | Niles | Illinois | 60714 | — |
| Community Clinical Research Center | Anderson | Indiana | 46011 | — |
| Ft. Wayne Med Onco-Hema Inc | Fort Wayne | Indiana | 46845 | — |
| Cotton-O-Neil Clinical Research Center | Topeka | Kansas | 66606 | — |
| West KY Hematology Oncology Group PSC | Paducah | Kentucky | 42003 | — |
| Christus St. Francis Cabrini Cancer Center | Alexandria | Louisiana | 71301 | — |
| East Jefferson General Hospital | Metairie | Louisiana | 70006 | — |
| New England Cancer Specialists | Scarborough | Maine | 04074 | — |
| Anne Arundel Medical Center | Annapolis | Maryland | 21401 | — |
| University Of Maryland | Baltimore | Maryland | 21201 | — |
| Sinai Hospital Of Baltimore | Baltimore | Maryland | 21215 | — |
| Center For Cancer And Blood Disorders | Bethesda | Maryland | 20817 | — |
| Maryland Oncology Hematology, P.A. | Columbia | Maryland | 21044 | — |
| Bay Hematology Oncology | Easton | Maryland | 21601 | — |
| Cancer & Hematology Centers Of Western Michigan | Grand Rapids | Michigan | 49503 | — |
| Minnesota Oncology Hematology, P.A. | Edina | Minnesota | 55435 | — |
| Forrest General Cancer Center | Hattiesburg | Mississippi | 39401 | — |
| Jackson Oncology Associates, Pllc | Jackson | Mississippi | 39202 | — |
| St. Louis Cancer Care, Llp | Bridgeton | Missouri | 63044 | — |
| Saint Vincent Frontier Cancer Center | Billings | Montana | 59105 | — |
| Southeast Nebraska Cancer Center | Lincoln | Nebraska | 68510 | — |
| Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89128 | — |
| Hunterdon Medical Center | Flemington | New Jersey | 08822 | — |
| Summit Medical Group | Morristown | New Jersey | 07960 | — |
| Atlantic Health System | Summit | New Jersey | 07901 | — |
| Morristown Medical Center | Summit | New Jersey | 07901 | — |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | — |
| New York Oncology Hematology, Pc | Albany | New York | 12208 | — |
| Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| Broome Oncology | Johnson City | New York | 13790 | — |
| Northern Westchester Hospital | Mount Kisco | New York | 10549 | — |
| Columbia University Medical Center (Cumc) | New York | New York | 10032 | — |
| Hematology-Oncology Associates Of Rockland | Nyack | New York | 10960 | — |
| White Plains Hospital | White Plains | New York | 10601 | — |
| Cone Health Cancer Center | Greensboro | North Carolina | 27403 | — |
| Moses Cone Health System | Greensboro | North Carolina | 27403 | — |
| Randolph Cancer Center | Greensboro | North Carolina | 27403 | — |
| First Health Of The Carolinas | Pinehurst | North Carolina | 28374 | — |
| W.G. Bill Hefner VA Medical Center | Salisbury | North Carolina | 28144 | — |
| Cancer Care Center | Bismarck | North Dakota | 58501 | — |
| Sanford Health | Fargo | North Dakota | 58122 | — |
| Oncology Hematology Care, Inc. | Cincinnati | Ohio | 45242 | — |
| Louis Stokes Cleveland VA Medical Center | Cleveland | Ohio | 44106-1702 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Mid Ohio Oncology Hematology | Columbus | Ohio | 43219 | — |
| Oklahoma Cancer Specialists and Research Institute, LLC-Clinical Research | Tulsa | Oklahoma | 74146 | — |
| Oncology Associates Of Oregon, Pc | Eugene | Oregon | 97401 | — |
| Hematology Oncology Associates | Medford | Oregon | 97504 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| St. Luke's University Hospital Bethlehem | Bethlehem | Pennsylvania | 18015 | — |
| Erie Regional Cancer Center | Erie | Pennsylvania | 16505 | — |
| Abington Hematology Oncology Associates, Inc | Horsham | Pennsylvania | 18944 | — |
| Charleston Hematology Oncology Associates, Pa | Charleston | South Carolina | 29414 | — |
| Greenville Health System | Greenville | South Carolina | 29615 | — |
| Sanford Research | Sioux Falls | South Dakota | 57104 | — |
| Chattanooga Oncology Hematology Associates | Chattanooga | Tennessee | 37404 | — |
| The Jones Clinic, PC | Germantown | Tennessee | 38138 | — |
| West Cancer Center | Germantown | Tennessee | 38138 | — |
| Tennessee Oncology, PLLC - SCRI - PPDS | Nashville | Tennessee | 37203 | — |
| Texas Oncology-Abilene | Abilene | Texas | 79606 | — |
| Texas Oncology - Amarillo | Amarillo | Texas | 79106 | — |
| Texas Oncology-Arlington North | Arlington | Texas | 76012 | — |
| Texas Oncology-Central Austin Cancer Center | Austin | Texas | 78745 | — |
| Texas Oncology-Beaumont | Beaumont | Texas | 77702 | — |
| Texas Oncology | Bedford | Texas | 76022 | — |
| Texas Oncology/Methodist Charlton Cancer Ctr | Dallas | Texas | 75203 | — |
| Texas Oncology | Dallas | Texas | 75230 | — |
| Texas Oncology | Dallas | Texas | 75231 | — |
| Texas Oncology, P.A. | Dallas | Texas | 75246 | — |
| Texas Oncology | Denton | Texas | 76201 | — |
| Texas Oncology | El Paso | Texas | 79902 | — |
| Texas Oncology | Flower Mound | Texas | 75028 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | — |
| Texas Oncology | Fort Worth | Texas | 76104 | — |
| The Center For Cancer And Blood Disorders | Fort Worth | Texas | 76104 | — |
| Texas Oncology | Houston | Texas | 77024 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Texas Cancer Center Of Mesquite | Mesquite | Texas | 75150 | — |
| Texas Oncology, Pa | Midland | Texas | 79701 | — |
| Texas Oncology | New Braunfels | Texas | 78130 | — |
| Texas Oncology | Paris | Texas | 75460 | — |
| Texas Oncology-Plano East | Plano | Texas | 75075-7787 | — |
| Texas Oncology Plano West Cancer Center | Plano | Texas | 75093 | — |
| Cancer Centers of South Texas | San Antonio | Texas | 78212 | — |
| Texas Cancer Center - Sherman | Sherman | Texas | 75090 | — |
| Texas Oncology Cancer Center - Sugar Land | Sugar Land | Texas | 77479 | — |
| Texas Oncology-Tyler | Tyler | Texas | 75702 | — |
| Texas Oncology Cancer Care And Research Center | Waco | Texas | 76712 | — |
| Texas Oncology, P.A. | Webster | Texas | 77598-4420 | — |
| Texas Oncology | Weslaco | Texas | 78596 | — |
| Texas Oncology-Wichita Falls | Wichita Falls | Texas | 76310 | — |
| Oncology & Hematology Associates Of Southwest Virginia, Inc. | Blacksburg | Virginia | 24060 | — |
| Virginia Cancer Specialists, Pc | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Virginia Cancer Institute | Richmond | Virginia | 23230 | — |
| Shenandoah Oncology | Winchester | Virginia | 22601 | — |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | — |
| Cancer Care Northwest | Spokane Valley | Washington | 99216 | — |
| Northwest Cancer Specialists, Pc | Vancouver | Washington | 98684 | — |
| Yakima Valley Memorial Hospital/North Star Lodge | Yakima | Washington | 98902 | — |
| Edwards Comprehensive Cancer Center | Huntington | West Virginia | 25701 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02574078, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2021 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02574078 live on ClinicalTrials.gov.