ClinicalTrials.gov record
Trial of Sacituzumab Govitecan in Participants With Refractory/Relapsed Metastatic Triple-Negative Breast Cancer (TNBC)
ClinicalTrials.gov ID: NCT02574455
Public ClinicalTrials.gov record NCT02574455. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 4, 2026, 7:11 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An International, Multi-Center, Open-Label, Randomized, Phase III Trial of Sacituzumab Govitecan Versus Treatment of Physician Choice in Patients With Metastatic Triple-Negative Breast Cancer Who Received at Least Two Prior Treatments
Study identification
- NCT ID
- NCT02574455
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Gilead Sciences
- Industry
- Enrollment
- 529 participants
Conditions and interventions
Conditions
Interventions
- Capecitabine Drug
- Eribulin Drug
- Gemcitabine Drug
- Sacituzumab govitecan Drug
- Vinorelbine Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 6, 2017
- Primary completion
- Mar 29, 2020
- Completion
- Dec 7, 2020
- Last update posted
- Jun 14, 2022
2017 – 2020
United States locations
- U.S. sites
- 185
- U.S. states
- 25
- U.S. cities
- 147
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Cancer Center, 29653 Anchor Cross Blvd | Daphne | Alabama | 36526 | — |
| Souther Cancer Center, 3719 Dauphin St., 5 Floor | Mobile | Alabama | 36608 | — |
| Southern Cancer Center, 3 Mobile Infirmary Circle | Mobile | Alabama | 36608 | — |
| Southern Cancer Center, 6701 Airport Blvd., Bldg B, Terace Level | Mobile | Alabama | 36608 | — |
| Mayo Clinic Hospital | Phoenix | Arizona | 85054 | — |
| Mayo Clinic Hospital | Scottsdale | Arizona | 85259 | — |
| UCLA Jonsson Comprehensive Cancer Center, 1411 S. Garfield Ave Suite 200 | Alhambra | California | 91801 | — |
| UCLA Jonsson Comprehensive Cancer Center, 201. S. Buena Vista St Suite 200 | Burbank | California | 91505 | — |
| UCLA Jonsson Comprehensive Cancer Center | Laguna Hills | California | 92653 | — |
| UCLA Jonsson Comprehensive Cancer Center, 200 UCLA Medical Plaza | Los Angeles | California | 90095 | — |
| UCLA Jonsson Comprehensive Cancer Center, 625 South Fair Oaks Avenue Suite 320 | Pasadena | California | 91105 | — |
| University of California, San Francisco (UCSF) - Innovation, Technology & Alliances, 1600 Divisadero Street | San Francisco | California | 94115 | — |
| UCLA Jonsson Comprehensive Cancer Center, 2020 Santa Monica Boulevard | Santa Monica | California | 94115 | — |
| Rocky Mountain Cancer Centers, 1700 South Potomac Street | Aurora | Colorado | 80012-5405 | — |
| University of Colorado Hospital - Anschutz Cancer Pavilion, 1665 Aurora Court | Aurora | Colorado | 80045 | — |
| Rocky Mountain Cancer Centers, 4715 Arapahoe Ave | Boulder | Colorado | 80303 | — |
| Rocky Mountain Cancer Centers, 2312 N. Nevada Avenue, Suite 400 | Colorado Springs | Colorado | 80907 | — |
| Rocky Mountain Cancer Centers, 1800 Williams St. | Denver | Colorado | 80218 | — |
| Rocky Mountain Cancer Centers, 4700 E. Hale Parkway, Suite 400 | Denver | Colorado | 80220 | — |
| Rocky Mountain Cancer Centers, 499 E Hampden Ave Suite 450 | Englewood | Colorado | 80113 | — |
| Rocky Mountain Cancer Centers, 11750 West 2nd Place, Suite 1-100 | Lakewood | Colorado | 80228 | — |
| Rocky Mountain Cancer Centers, 22 West Dry Creek Circle | Littleton | Colorado | 80120 | — |
| Rocky Mountain Cancer Centers, 10103 Ridge Gate Parkway, Suite G-01 | Lone Tree | Colorado | 80124 | — |
| Rocky Mountain Cancer Centers, 2030 W Mountain View Avenue, Ste. 210 | Longmont | Colorado | 80501 | — |
| Rocky Mountain Cancer Centers, 9397 Crown Crest Blvd., Suite 421 | Parker | Colorado | 80138 | — |
| Rocky Mountain Cancer Centers, 3676 Parker Blvd., Suite 350 | Pueblo | Colorado | 81008 | — |
| Rocky Mountain Cancer Centers, 8820 Huron Street | Thornton | Colorado | 80260 | — |
| Yale School Of Medicine | New Haven | Connecticut | 06510-3206 | — |
| Norwalk Hospital, 34 Maple Street | Norwalk | Connecticut | 06856 | — |
| Georgetown Lombardi Comprehensive Cancer Center | Washington D.C. | District of Columbia | 20007 | — |
| Florida Cancer Specialists & Research Institute, 601 E. Altamonte Drive | Altamonte Springs | Florida | 32701 | — |
| Florida Cancer Specialist | Bonita Springs | Florida | 34135 | — |
| Florida Cancer Specialists | Bradenton | Florida | 34209 | — |
| Florida Cancer Specialists & Research Institute, 403 S. King Ave | Brandon | Florida | 33511 | — |
| Florida Cancer Specialists | Cape Coral | Florida | 33914 | — |
| Florida Cancer Specialists & Research Institute, 3280 McMullen Booth road | Clearwater | Florida | 33761 | — |
| Sylvester Comprehensive Cancer Center | Coral Gables | Florida | 33146 | — |
| Florida Cancer Specialists & Research Institute, 224 Memorial medical Parway | Daytona Beach | Florida | 32117 | — |
| Sylvester Comprehensive Cancer Center | Deerfield Beach | Florida | 33442 | — |
| Florida Cancer Specialists | Fort Myers | Florida | 33905 | — |
| Florida Cancer Specialists & Research Institute, 6420 W Newberry Road Est Wing | Gainesville | Florida | 32605 | — |
| Florida Cancer Specialists & Research Institute, 100 Highland Avenue | Largo | Florida | 33770 | — |
| Florida Cancer Specialists & Research Institute, 521 N. Lecanto Highway | Lecanto | Florida | 34461 | — |
| Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | — |
| Baptist Health Medical Group Oncology, LLC | Miami | Florida | 33176 | — |
| Florida Cancer Specialists | Naples | Florida | 34102 | — |
| Florida Cancer Specialists & Research Institute, 8763 River Crossing Blvd | New Port Richey | Florida | 34655 | — |
| Florida Cancer Specialists & Research Institute, 1630 SE 18th ST | Ocala | Florida | 34471 | — |
| Florida Cancer Specialists & Research Institute, 765 Image Way | Orange City | Florida | 32763 | — |
| Orlando Regional Medical Center | Orlando | Florida | 32806-2008 | — |
| Florida Cancer Specialists & Research Institute, 70 W Gore Street | Orlando | Florida | 32806 | — |
| Florida Cancer Specialists & Research Institute - 325 Clyde Morris | Ormond Beach | Florida | 32774 | — |
| Sylvester Comprehensive Cancer Center | Plantation | Florida | 33324 | — |
| Florida Cancer Specialists | Port Charlotte | Florida | 33980 | — |
| Florida Cancer Specialists | Sarasota | Florida | 34236 | — |
| Florida Cancer Specialists & Research Institute, 7154 Medical Center Drive | Spring Hill | Florida | 34608 | — |
| Florida Cancer Specialists & Research Institute, 1201 Fifth Avenue North | St. Petersburg | Florida | 33705-1449 | — |
| Florida Cancer Specialists & Research Institute, 560 Jackson St | St. Petersburg | Florida | 33705 | — |
| Florida Cancer Specialists & Research Institute, 3402 W Dr. Martin Luther King Jr Boulevard | Tampa | Florida | 33607 | — |
| Florida Cancer Specialists & Research Institute, 4100 Waterman Way | Tavares | Florida | 32778 | — |
| Florida Cancer Specialists & Research Institute, 1400 US highway 441 N | The Villages | Florida | 32159 | — |
| Florida Cancer Specialists | Venice | Florida | 34285 | — |
| Florida Cancer Specialists | Venice | Florida | 34292 | — |
| Florida Cancer Specialists & Research Institute - 3730 7th Terrace | Vero Beach | Florida | 32960 | — |
| Florida Cancer Specialists & Research Institute, 1037 State Road 7 Bldg B | Wellington | Florida | 98374 | — |
| Florida Cancer Specialists & Research Institute1309 N Flagler Dr | West Palm Beach | Florida | 33401-3406 | — |
| Florida Cancer Specialists & Research Institute, 2100 Glenwood Drive | Winter Park | Florida | 32792 | — |
| Atlanta Cancer Center - Alpharetta | Alpharetta | Georgia | 30005 | — |
| University Cancer & Blood Center, 3320 Old Jefferson Rd | Athens | Georgia | 30607 | — |
| GCS/Annex | Atlanta | Georgia | 30341 | — |
| Atlanta Cancer Care - Atlanta | Atlanta | Georgia | 30342 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| GCS/Canton | Canton | Georgia | 30114 | — |
| Atlanta Cancer Care - Conyers | Conyers | Georgia | 30094 | — |
| Atlanta Cancer Care - Cumming | Cumming | Georgia | 30041 | — |
| Atlanta Cancer Care - Decatur | Decatur | Georgia | 30033 | — |
| GCS/Stemmer | Decatur | Georgia | 30033 | — |
| Atlanta Cancer Care - Stockbridge | Jonesboro | Georgia | 30236 | — |
| GCS/Macon | Macon | Georgia | 31217 | — |
| GCS/Kennestone | Marietta | Georgia | 30060 | — |
| GCS/Northside | Sandy Springs | Georgia | 30342 | — |
| Illinois Cancer Specialists | Arlington Heights | Illinois | 60005 | — |
| University of Chicago Medical Center 5841 S. Maryland Ave | Chicago | Illinois | 60637 | — |
| University of Chicago Comprehensive Cancer Center at Silver Cross Hospital 1900 Silver Cross Blvd | New Lenox | Illinois | 60451 | — |
| Illinois Cancer Specialists | Niles | Illinois | 60714-5905 | — |
| Orland Park - UCMC Center for Advanced Care 14290 South LaGrange Rd | Orland Park | Illinois | 60462 | — |
| MidAmerica Division Inc. c/o Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| University of Kansas Cancer Center - The Richard and Annette Bloch Cancer Care Pavilion | Westwood | Kansas | 66205-2005 | — |
| Maryland Oncology Hematology | Bethesda | Maryland | 20817 | — |
| Maryland Oncology Hematology | Brandywine | Maryland | 20613 | — |
| Maryland Oncology Hematology | Clinton | Maryland | 20735 | — |
| Maryland Oncology Hematology | Columbia | Maryland | 21044 | — |
| Maryland Oncology Hematology | Rockville | Maryland | 20850 | — |
| Maryland Oncology Hematology | Silver Spring | Maryland | 20902 | — |
| Maryland Oncology Hematology | Silver Spring | Maryland | 20904 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02114-2621 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center (BIDMC) | Boston | Massachusetts | 02215-5400 | — |
| Mass General - North Shore Cancer Center ( NSCC ) | Danvers | Massachusetts | 01923 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Minnesota Oncology Hematology P.A. | Coon Rapids | Minnesota | 55433 | — |
| Suburban Imaging Northwest | Coon Rapids | Minnesota | 55433 | — |
| Suburban Imaging | Coon Rapids | Minnesota | 55433 | — |
| Mercy Hospital - Unity Campus AHL | Fridley | Minnesota | 55432 | — |
| Minnesota Oncology Hematology P.A. | Fridley | Minnesota | 55432 | — |
| Minnesota Oncology Hematology P.A. | Minneapolis | Minnesota | 55404 | — |
| Abbot Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Virginia G. Piper Cancer Center at HonorHealth | Minneapolis | Minnesota | 55407 | — |
| Mayo Clinic - 200 First Street SW | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine in St. Louis | Creve Coeur | Missouri | 63141 | — |
| MidAmerica Division Inc. c/o Menorah Medical Center | Independence | Missouri | 64057 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Washington University School of Medicine in St. Louis | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine in St. Louis | St Louis | Missouri | 63129 | — |
| Washington University School of Medicine in St. Louis | St Louis | Missouri | 63136 | — |
| Nebraska Cancer Specialists - Midwest Cancer Center - Papillion | Omaha | Nebraska | 68114 | — |
| Nebraska Cancer Specialists - Midwest Cancer Center - Paillion | Omaha | Nebraska | 68130 | — |
| Nebraska Cancer Specialists- Midwest Cancer Center- Papillion | Papillion | Nebraska | 68046-5706 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| New York Oncology Hematology, P.C. | Albany | New York | 12206 | — |
| New York Oncology Hematology, P.C. | Clifton Park | New York | 12065 | — |
| North Shore Hematology Oncology Associates., PC, 235 North Belle Mead Road | East Setauket | New York | 11733 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| North Shore Hematology Oncology Associates., PC, 285 Sills Road Building 16 | Patchogue | New York | 11772 | — |
| UNC Health Care System | Chapel Hill | North Carolina | 27599 | — |
| The Ohio State University Wexner Medical Center, 460 W 10th Ave | Columbus | Ohio | 432100 | — |
| The Ohio State University Wexner Medical Center, 1145 Olentangy River Road | Columbus | Ohio | 43212 | — |
| Providence Medical Group | Portland | Oregon | 97213 | — |
| UPMC Hillman Cancer Center Mountainview Arnold Palmer Pavilion | Greensburg | Pennsylvania | 15601 | — |
| UPMC Hillman Cancer Center UPMC East | Monroeville | Pennsylvania | 15146 | — |
| UPMC Hillman Cancer Center Upper Saint Clair | Pittsburgh | Pennsylvania | 15102 | — |
| Allegheny-Singer Research Institute, 320 East North Avenue | Pittsburgh | Pennsylvania | 15212 | — |
| Magee-Womens Hospital of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC Hillman Cancer Center UPMC Passavant | Pittsburgh | Pennsylvania | 15237 | — |
| Tennessee Oncology - Chattanooga Oncology & Hematology Associates | Chattanooga | Tennessee | 37404-1108 | — |
| Tennesee Oncology - PLLC | Chattanooga | Tennessee | 37404 | — |
| Tenesse Oncology - PLLC | Cleveland | Tennessee | 37311 | — |
| Tennessee Oncology, LLC | Dickson | Tennessee | 37055 | — |
| Tennessee Ocology, LLC | Franklin | Tennessee | 37067 | — |
| Tennessee Oncology, LLC | Gallatin | Tennessee | 37066 | — |
| West Cancer Center, 7945 Wolf River Blvd | Germantown | Tennessee | 28138 | — |
| Tennessee Oncology, LLC | Hermitage | Tennessee | 37076 | — |
| Tennessee Oncology, LLC | Lebanon | Tennessee | 37090 | — |
| Tennessee Oncology, LLC | Murfreesboro | Tennessee | 37129 | — |
| Sarah Cannon Cancer Institute/Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| Tennessee Oncology, LLC | Nashville | Tennessee | 37203 | — |
| Vanderbilt Breast Cancer Center at One Hundred Oaks 719 Thompson Lane, Suite 25000 | Nashville | Tennessee | 37204 | — |
| Tennessee Ocology, LLC | Nashville | Tennessee | 37205 | — |
| Tennessee Oncology, LLC | Nashville | Tennessee | 37207 | — |
| Tenessee Oncology | Nashville | Tennessee | 37211 | — |
| Henry-Joyce Cancer Clinic 1301 Medical Center Drive 1903 The Vanderbilt Clinic Nashville, TN 37232 | Nashville | Tennessee | 37232 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| Tennessee Oncology, LLC | Shelbyville | Tennessee | 37160 | — |
| Center for Cancer and Blood Disorders | Arlington | Texas | 76014 | — |
| Center for Cancer and Blood Disorders | Burleson | Texas | 76028 | — |
| Texas Oncology- Medical City Dallas Building D | Dallas | Texas | 75230-6899 | — |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246-2006 | — |
| Texas Oncology | Denton | Texas | 76210 | — |
| Center for Cancer and Blood Disorders | Fort Worth | Texas | 76104-4611 | — |
| Houston Methodist Hospital - 6565 Fannin St | Houston | Texas | 77030 | — |
| Texas Oncology-Longview Cancer Center | Longview | Texas | 75601 | — |
| Texas Oncology | Plano | Texas | 75075-7753 | — |
| US Oncology | Tyler | Texas | 75702 | — |
| Center for Cancer and Blood Disorders | Weatherford | Texas | 76086 | — |
| Virginia Cancer Specialists, PC | Alexandria | Virginia | 22304 | — |
| Virginia Cancer Specialists, PC | Arlington | Virginia | 22205 | — |
| Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Blacksburg | Virginia | 24060 | — |
| Virginia Oncology Associates | Chesapeake | Virginia | 23320 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031-4629 | — |
| Virginia Cancer Specialists, PC | Gainesville | Virginia | 20155 | — |
| Virginia Oncology Associates | Hampton | Virginia | 23666 | — |
| Virginia Cancer Specialists, PC | Leesburg | Virginia | 20176 | — |
| Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Low Moor | Virginia | 24457 | — |
| Virginia Oncology Associates | Newport News | Virginia | 23606 | — |
| Virginia Oncology Associates, P.C. | Norfolk | Virginia | 23502-0026 | — |
| Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Roanoke | Virginia | 24014 | — |
| Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Salem | Virginia | 24153 | — |
| Virginia Oncology Associates | Virginia Beach | Virginia | 23456 | — |
| Virginia Cancer Specialists, PC | Woodbridge | Virginia | 22191 | — |
| Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Wytheville | Virginia | 24382 | — |
| Swedish Cancer Institute | Edmonds | Washington | 98026 | — |
| Swedish Cancer Institute | Issaquah | Washington | 98029 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Swedish Cancer Institute | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02574455, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 14, 2022 · Synced May 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT02574455 live on ClinicalTrials.gov.